USMLE paper 2
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Bone Marrow failure due to hematopoietic stem cell deficiency Causes: -Autoimmune -Infections (Parvo B-19, EBV) -Drugs (Carbamazepine, Chloramphenicol, Sulfonamides) -Exposure to radiation or toxins (benzene, solvents) Pancytopenia: -Anemia (fatigue, weak, pallor) -Thrombocytopenia (mucosal bleeding, easy bruising, petechiae) -Leukopenia (recurrent infections) BIOPSY: Hypocellular bone marrow with fat and stromal cells - Answer infant with pallor, fatigue, easy bruising/bleeding, petec...
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Bone Marrow failure due to hematopoietic stem cell deficiency Causes: -Autoimmune -Infections (Parvo B-19, EBV) -Drugs (Carbamazepine, Chloramphenicol, Sulfonamides) -Exposure to radiation or toxins (benzene, solvents) Pancytopenia: -Anemia (fatigue, weak, pallor) -Thrombocytopenia (mucosal bleeding, easy bruising, petechiae) -Leukopenia (recurrent infections) BIOPSY: Hypocellular bone marrow with fat and stromal cells - Answer infant with pallor, fatigue, easy bruising/bleeding, petec...