NURS 5315
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Advanced Pathophysiology NURS 5350 Exam 3 
What is a cough? 
 
Protective reflex that helps clear the airways by an explosive expiration. 
 
Acute cough: 2-3 weeks 
 
Chronic cough: longer than 3 weeks. 
 
Causes: Post nasal drip, GERD, medications (ACE). 
 
 
 
Hypoventilation vs. Hyperventilation? 
 
Hypo: Alveolar ventilation is INADEQUATE: leads to RESPIRATORY ACIDOSIS. 
 
Hyper: Alveolar ventilation EXCEEDS metabolic demands: Leads to RESPIRATORY ALKALOSIS. 
 
 
 
What is clubbing? 
 
A pai...
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Advanced Pathophysiology NURS 5350 Exam 3 
What is a cough? 
 
Protective reflex that helps clear the airways by an explosive expiration. 
 
Acute cough: 2-3 weeks 
 
Chronic cough: longer than 3 weeks. 
 
Causes: Post nasal drip, GERD, medications (ACE). 
 
 
 
Hypoventilation vs. Hyperventilation? 
 
Hypo: Alveolar ventilation is INADEQUATE: leads to RESPIRATORY ACIDOSIS. 
 
Hyper: Alveolar ventilation EXCEEDS metabolic demands: Leads to RESPIRATORY ALKALOSIS. 
 
 
 
What is clubbing? 
 
A pai...
NURS 5315 Advanced Pathophysiology-Exam 3 
1. Explain the cardiac structure and blood flow through chambers/valves. 
 
The right atrium receives ______ blood from the body. 
deoxygenated 
 
 
1. Explain the cardiac structure and blood flow through chambers/valves. 
 
Blood travels from the right atrium, through the ______ valve, to the right ventricle. From the right ventricle, blood travels through the _____ valve and into the ____ artery 
tricuspid, pulmonic, pulmonary 
 
 
1. Explain the card...
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NURS 5315 Advanced Pathophysiology-Exam 3 
1. Explain the cardiac structure and blood flow through chambers/valves. 
 
The right atrium receives ______ blood from the body. 
deoxygenated 
 
 
1. Explain the cardiac structure and blood flow through chambers/valves. 
 
Blood travels from the right atrium, through the ______ valve, to the right ventricle. From the right ventricle, blood travels through the _____ valve and into the ____ artery 
tricuspid, pulmonic, pulmonary 
 
 
1. Explain the card...
NURS 5315 Advanced Pathophysiology 
Ovarian cancer site of metastasis? 
Peritoneal surfaces, omentum (fold of peritoneum connecting the stomach with other abdominal organs), liver 
 
 
The increased NADH/NAD+ ratio in the liver from ethanol causes: 
1. Pyruvate --> lactic acid, causing lactic acidosis 
2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to hypoglycemia 
3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines with fatty acids to form triglyce...
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NURS 5315 Advanced Pathophysiology 
Ovarian cancer site of metastasis? 
Peritoneal surfaces, omentum (fold of peritoneum connecting the stomach with other abdominal organs), liver 
 
 
The increased NADH/NAD+ ratio in the liver from ethanol causes: 
1. Pyruvate --> lactic acid, causing lactic acidosis 
2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to hypoglycemia 
3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines with fatty acids to form triglyce...
NURS 5315 Advanced Pathophysiology 
Clinical implication for Beta blockers? (book) 
Atrial fibrillation, chronic left heart failure or reduced ejection fraction 
 
 
 
Beta Blockers (book) 
reduce myocardial demand. By blocking beta receptors. 
 
 
 
Myocardial contractility is a change in developed tension at a given resting fiber length, which is simply the ability of the heart muscle to shorten. At the molecular level, thin filaments of actin slide over thick filaments of myosin called the cr...
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NURS 5315 Advanced Pathophysiology 
Clinical implication for Beta blockers? (book) 
Atrial fibrillation, chronic left heart failure or reduced ejection fraction 
 
 
 
Beta Blockers (book) 
reduce myocardial demand. By blocking beta receptors. 
 
 
 
Myocardial contractility is a change in developed tension at a given resting fiber length, which is simply the ability of the heart muscle to shorten. At the molecular level, thin filaments of actin slide over thick filaments of myosin called the cr...
NURS 5315 FINAL EXAM|Latest Update Graded A+ 
Anion gap level 
Normal range is 3-10 
 
 
Osmol gap normal range and heat does an elevated value mean 
Normal range is <10 mOsm/kg; elevated levels indicate ethyl alcohol (etoh) consumption 
 
 
What triggers renin releases 
Triggered by dehydration; involved in the regulation of blood pressure 
 
 
What does a cirrhosis and HF do to oncotic pressure 
Increased in cirrhosis; decreased in heart failure 
 
 
What does an elevated serum osmolality p...
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NURS 5315 FINAL EXAM|Latest Update Graded A+ 
Anion gap level 
Normal range is 3-10 
 
 
Osmol gap normal range and heat does an elevated value mean 
Normal range is <10 mOsm/kg; elevated levels indicate ethyl alcohol (etoh) consumption 
 
 
What triggers renin releases 
Triggered by dehydration; involved in the regulation of blood pressure 
 
 
What does a cirrhosis and HF do to oncotic pressure 
Increased in cirrhosis; decreased in heart failure 
 
 
What does an elevated serum osmolality p...
NURS 5315: Advanced Patho Exam 5|Latest Update Graded A+ 
What are the key functions of the kidneys? 
Excretion of metabolic waste. 
Regulation of water and electrolyte balance 
Regulation of arterial BP 
Erythrocyte production 
1, 25 -dihyydroxy vitamin production (calcitriol) 
Gluconeogenesis 
 
 
What metabolic waste do the kidneys excrete? 
Urea 
Creatinine 
Bilirubin 
Drugs 
Hormone metabolites 
 
 
How do the kidneys regulate arterial blood pressure? 
RAAS 
 
The renin-angiotensin-aldoster...
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NURS 5315: Advanced Patho Exam 5|Latest Update Graded A+ 
What are the key functions of the kidneys? 
Excretion of metabolic waste. 
Regulation of water and electrolyte balance 
Regulation of arterial BP 
Erythrocyte production 
1, 25 -dihyydroxy vitamin production (calcitriol) 
Gluconeogenesis 
 
 
What metabolic waste do the kidneys excrete? 
Urea 
Creatinine 
Bilirubin 
Drugs 
Hormone metabolites 
 
 
How do the kidneys regulate arterial blood pressure? 
RAAS 
 
The renin-angiotensin-aldoster...
Advanced Pathophysiology NURS 5315 Test 2 
natural immunity 
immunity that we are born with 
 
 
Natural Immunity barriers 
skin, mucus membrane, natural killer cells, protein 
 
 
What protiens are associated with our natural immunity barriers? 
Cytokines and complements 
 
 
Phagocytic cells 
Neutrophils, macrophages, dendritic cells 
 
 
Neutraphils 
Associated with acute inflammation 
 
 
macrophages 
cells formed from monocytes that leave the blood stream 
 
 
Dendritic cells 
engulfs antig...
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Advanced Pathophysiology NURS 5315 Test 2 
natural immunity 
immunity that we are born with 
 
 
Natural Immunity barriers 
skin, mucus membrane, natural killer cells, protein 
 
 
What protiens are associated with our natural immunity barriers? 
Cytokines and complements 
 
 
Phagocytic cells 
Neutrophils, macrophages, dendritic cells 
 
 
Neutraphils 
Associated with acute inflammation 
 
 
macrophages 
cells formed from monocytes that leave the blood stream 
 
 
Dendritic cells 
engulfs antig...
Advanced Patho NURS 5315 exam 1 
action potential 
The process by which excitable cells transmit information from one to another. 
 
 
How is the action potential altered by a potassium imbalance? (Hyperkalemia) 
The ECF has more K+ ions. The membrane potential becomes more positive (hypopolarized). 
Cells become MORE excitable. 
T waves peak. 
QRS complexes widen. 
Causes dysrhythmias, weakness, paresthesia. 
{If membrane potential becomes equal to threshold potential cardiac standstill occurs}...
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Advanced Patho NURS 5315 exam 1 
action potential 
The process by which excitable cells transmit information from one to another. 
 
 
How is the action potential altered by a potassium imbalance? (Hyperkalemia) 
The ECF has more K+ ions. The membrane potential becomes more positive (hypopolarized). 
Cells become MORE excitable. 
T waves peak. 
QRS complexes widen. 
Causes dysrhythmias, weakness, paresthesia. 
{If membrane potential becomes equal to threshold potential cardiac standstill occurs}...
initial repolarization of cells 
voltage gated sodium channels closed 
voltage gated potassium channels open 
Potassium leaves cell slowly
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initial repolarization of cells 
voltage gated sodium channels closed 
voltage gated potassium channels open 
Potassium leaves cell slowly
NURS 5315 FINAL EXAM LATEST 2024 QUESTIONS & ANSWERS WITH RATIONALE
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NURS 5315 FINAL EXAM LATEST 2024 QUESTIONS & ANSWERS WITH RATIONALE