Genetics
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Latest content Genetics
Which term or phrase is used to describe the ability of the environment to cause different phenotypes to develop from the same genotype? 
 
A. Developmental plasticity 
B. Histone modification 
C. Phenotype variability 
D. Nutrigenomics 
A. Developmental plasticity 
How is alcohol consumption thought to increase methylation in cancer suppressor genes to increase the risk for head and neck cancer? 
 
A. Preventing DNA repair 
B. Enhancing cell division 
C. Acting as a methyl donor 
D. Activating ...
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DNA fragments cut by restriction enzymes can form two types of ends. What are these ends called? 
Sticky and blunt ends 
The restriction enzyme HincII was isolated from the bacterium Haemophilas influenza. The DNA sequence cut by this enzyme is shown here. (Note that Y means any pyrimidine--C or T--and that R means any purine--A or G.) 
 
CTY*RAC 
GAR*YTG 
 
HincII is a blunt-end cutter that cuts after the Y. 
The lambda phage genome is 48.5 kb in size and has 50% GC content. 
Approximately how ...
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What are 3 ways to improve GWAS? 
- more power -> increase sample size, increase effect 
- better chip design or sequencing to detect rarer variants 
- better case vs control definition -> e.g. some control may have hypertension (ht) but not identified and the study may be looking at genome for ht 
What would it mean if HT had fewer risk alleles of larger effect sizes than other complex phenotypes? 
identification of susceptible variants for ht is likely to be reliant on synthesis of findi...
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The principles of dominance, segregation, and independent assortment were first described by 
A. Darwin 
B. Waston and Crick 
C. Lamarck 
D. Mendel 
Gregor Mendel developed some basic principles of heredity based on his 
(1) dissection of the flowers of both tall and short African violet plants 
(2) microscopic observation of the nuclei of fruit fly cells 
(3) biochemical analysis of DNA produced in the F2 generations of roan cattle 
(4) mathematical analysis of the offspring produced by crossin...
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Why do scientists think that all forms of life on earth have a common origin? 
 
All living organisms use the same genetic code 
Related genes from different organisms have similar nucleotide sequences 
Different organisms have related genes with similar functions 
Related genes from different organisms have similar amino acid sequences 
All the choices are correct 
All the choices are correct 
If an Ss x Ss mating is performed and the progeny have the following phenotypic ratios of 3 S_ , (- in...
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The two strands of DNA are said to be ___ to each other since adenine is always across the molecule from thymine and cytosine is always across the molecule from guanine. Pick the best answer. 
Complementary 
The nucleotides along each strand of DNA are joined by ____ bonds. 
 
___ bonds join one nucleotide to the next along a strand of RNA. 
Phosphodiester 
Is the helical coiling shown in this picture a right-handed or left-handed coil? 
Right-Handed Coil 
X-ray diffraction experiments conducted...
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What does DNA stand for? 
Deoxyribonucleic acid 
Segments of DNA which code for specific proteins are called... 
Genes 
DNA may coil and condense into visible structures called... 
Chromosomes 
How many nitrogenous bases are found in DNA? 
Four 
What two nitrogenous bases are purines? 
Adenine and Guanine 
What two nitrogenous bases are pyrimidines? 
Cytosine and Thymine 
Adenine always pairs with... 
Thymine 
Cytosine always pairs with... 
Guanine 
What chemical bond holds the nitrogenous base ...
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The roads are information stored inside the 
Nucleus which is chromosomes that contain many genes 
The largest amount of DNA in a plant cell is contained in 
A nucleus 
Genes involved in the production of abnormal red blood cells have an abnormal sequence of 
Bases 
The diagram below represents an incomplete section of DNA molecule. The boxes represent unified basis. What will be the total number of bases represented by the letter A( both inside and outside the boxes) when the boxes are complete...
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Which would NOT be an effective way to diagnose sickle cell anemia? 
A Enzymatic assay for hemoglobin activity. 
B PCR exon 1 of the b-globin gene, followed by ASO hybridization with oligonucleotides specific for normal and betaS alleles. 
C Restriction digest of genomic DNA with MstII, followed by Southern blot, using a b-globin gene product. 
D PCR exon 1 of the b-globin gene, followed by restriction digest with MstII. 
E Hemoglobin electrophoresis. 
A 
All of the following provide supporting ...
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genetics 
scientific study of heredity (the delivery of characteristics from parent to offspring) 
fertilization 
process in sexual reproduction in which male and female reproductive cells (gametes) join to form a new cell 
trait 
specific characteristics of an individual 
hybrid 
offspring of crosses between parents with different traits 
gene 
a factor that is passed from parent to offspring; sequence of DNA that codes for a protein and thus determines a trait 
allele 
one of a number of diffe...
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A pea plant heterozygous for height and seed color (TtYy) is crossed with a pea plant heterozygous for height but homozygous for seed color (Ttyy). If 80 offspring are produced, how many are expected to be tall and have yellow seeds? 
30 offspring 
How many sets of chromosomes are in a diploid cell? 
Two sets 
The gene map of a fruit fly's chromosomes shows the relative locations of the star eye, dumpy wing, and black body genes to be 1.3, 13.0, and 48.5. Between which two genes does crossing...
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genetics 
The scientific study of heredity, or delivery 
of characteristics from parent to offspring, known as _____ is the key to understanding 
what makes each organism unique. 
Gregor Mendel 
Concluded that traits are inherited through the passing of factors from parents to offspring. 
fertilization 
During sexual reproduction, male and female reproductive cells join in a process known as ________ to produce a new cell. 
True breeding 
"____________," meaning that they were self- 
polli...
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Which statement describes the offspring of the F1 generation when crossing a pea plant that is true breeding for green seeds with a pea plant that is true breeding for yellow seeds? 
The offspring will inherit one allele from each parent. 
What is a gene? 
A section of DNA 
Some people have freckles, and some people do not have freckles. If a child has freckles, at least one parent has freckles. However, the child may have a sibling that does not have freckles. Which statement best describes the...
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Genetics 
The study of heredity 
Gregor Mendel 
The father of modern genetics 
Chromosomes 
found in the nucleus and carry genes 
1822 
Year Gregor Mendel was born 
pea plants 
plant studied by Gregor Mendel 
Genotype 
The genetic makeup of an organism 
Alleles 
varients or differences in a gene 
Phenotype 
An organism's physical appearance, or visible traits. 
Dominant
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Mendel was able to study seven traits in all the pea plants in each generation. Which of his hypotheses allowed him to analyze each trait separately? 
Wrong. For each inherited trait, there is only one copy of the gene that codes for that trait. 
If a scientist wanted to follow Mendel's experiment with a different kind of plant, which type of plant would she examine? 
A plant that has only two alleles for a trait.
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Which is the best example of a hypothesis leading to new experimental methods? 
Thomas Hunt Morgan continued the genetic research of Gregor Mendel, but Morgan used fruit flies. 
The table below summarizes the traits that Mendel examined during his experiments. 
 
Traits Studied by Mendel 
 
 
 
What do these characteristics all have in common? 
They can all be easily observed. 
Tall pea plants are dominant over short pea plants. If there are 200 short plants in the F2 generation from a cross tha...
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Cystic fibrosis is a genetic disorder. It is a recessive trait that is determined by two alleles. Suppose two parents each carry at least one recessive allele, but neither of them has cystic fibrosis. Which statement reflects the likelihood of a child of these parents having cystic fibrosis? 
The child may or may not have the disease because a recessive gene from each parent may be passed on. 
During an experiment, a scientist crosses a pea plant that has purple flowers with a pea plant that has...
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Tall pea plants are dominant over short pea plants. If there are 200 short plants in the F2 generation from a cross that followed Mendel's methods, about how many plants will be tall in that generation? 
600 
If Mendel had crossed a true breeding dominant plant with a true breeding recessive plant, in which of the three generations is the recessive trait visible? 
P generation and F2 generation 
If a scientist wanted to follow Mendel's experiment with a different kind of plant, which type ...
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Which statement describes Mendel's hypotheses regarding gametes? 
A gamete carries one allele for a gene. 
What controls traits and inheritance? 
nucleic acids 
Scientists often use fruit flies as a method to test hypotheses about human genes. Why are fruit flies advantageous in the study of human inheritance? 
They reproduce quickly and take up little space. 
The flowchart below shows the three generations of a cross between a pea plant that has yellow pods and a pea plant that has green pod...
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GENETICS TEST - EXTRA STUDY GUIDE 
INFO QUESTIONS WITH COMPLETE 
ANSWERS { GRADED A+} 
Any substance or chemical not naturally produced or found within an 
organism (ex: medications) - xenobiotic 
T/F? physiologic changes in pregnancy influence maternal absorption 
and distribution of drugs to fetus - TRUE 
increased maternal _______ prolongs gastric emptying time and slows 
intestinal motility impacting _____ circulation and absorption of 
xenobiotics which results in reduced peak materna...
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GENETICS•GENETICS