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AADE 23
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AADE STUDY QUESTIONS SET 3 
EXAM 2022 
A 38-year-old man with type 2 diabetes and an A1C of 8.7% stopped taking 
metformin 500mg twice daily due to persistent diarrhea. Which of the following is 
most likely to achieve his A1C goal of less than 7%? 
Liraglutide 
Canagliflozin 
Saxagliptin 
Glimepiride - Correct Answer- D - Glimepiride is correct. Biguanides and 
sulfonylureas lower A1C up to 2%, while other agents only lower A1C by 0.5% to 
1%, including: GLP-1 receptor agonists like liraglutide...
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