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Ion Channels - Sodium ion channels
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What are the different ion channel gating mechanisms?
What are the different ion channel gating mechanisms?
Voltage gated – change in membrane potential
Membrane stretch/ mechanical sensitive channels
Ligand gated - Binding of chemical mediator to internal part of the channel (e.g. ion channels open due to rise in Ca)
a) What are voltage gated sodium channels encoded by?
b) Which gene is encoded in the heart?
c) How many amino acids long are they on average?
a) What are voltage gated sodium channels encoded by?
b) Which gene is encoded in the heart?
c) H...
a) 9 genes = SCNA1-9
b) SCNA5
c)~2000 amino acids create a functional channel
What is the definition of channel closing?
What is the definition of channel closing?
Where the channel is not allowing ion flow due to the activation mechanism not being in place rather than because inactivation has occurred.
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