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Bacteriology & Virology - Bacteriophage
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What are bacteriophage?
What are bacteriophage?
Viruses that infect archaea & bacteria
How do phage with virulent life-styles infect bacteria?
How do phage with virulent life-styles infect bacteria?
Phage infect specific host bacterial cell via lytic cycle
Transcription/translation of phage proteins and replication of phage genome done using host machinery
The progeny phage are assembled from constituent parts, released by lysis of the host cell
Clear plaques on a petri dish
What are some beneficial uses of phage?
What are some beneficial uses of phage?
Phenotypic characterisation of bacterial strains (Phage typing)
Treatment of bacterial infections (Phage therapy)
Screening protein-ligand interactions (Phage display)
Source of novel enzymes - recombinant phage enzymes are a potential treatment for bacterial infections
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