Acute Kidney Injury is ____ and causes accumulation of _____, _____ imbalance, and ______
disturbances - Answers abrupt, waste, fluid, electrolyte
Kidneys produce hormones to control _____ and ____ function - Answers BP, RBC
AKI has reduced: ____ and _____ - Answers renal perfusion, GFR
Pre-renal AKI has decreased... - Answers blood flow
Intrinsic AKI is from injury to ____ - Answers tissue
Post-renal AKI is from... - Answers obstruction
Prolonged ischemia leads to... - Answers intrinsic AKI injury
What can cause pre-renal AKI? - Answers dehydration
hemorrhage
sepsis
heart failure
Reduced renal blood flow causes decreased _____ - Answers GFR
What are examples of intrinsic AKI injury? - Answers ATN
nephritis
nephrotoxins
What are causes of post-renal AKI? - Answers enlarged prostate
tumors
stones
What are risk factors for AKI? - Answers DM
HTN
heart disease
obesity
lupus
>60 age
,male
African American
Clinical manifestations of AKI include _____, elevated ____, fluid overload, hyper_____ and
hypo____, and fatigue - Answers oliguria, BUN, kalemia, natremia
What is the clinical progression of AKI? - Answers initiation, oliguric, diuretic, recovery
Chronic kidney disease is GFR of <____mL for 3 months - Answers 60
Chronic kidney disease results from loss of _____ - Answers nephrons
What are risk factors for chronic kidney disease? - Answers diabetes
high blood pressure
What are the 3 indicators of renal function? - Answers albuminuria
GFR
uremia
What is azotemia? - Answers early accumulation of nitrogenous wastes
_____ is a key indicator of GFR - Answers Creatine
What are early clinical manifestations of azotemia? - Answers fatigue, weakness, nausea,
apathy
What are progressive clinical manifestations of azotemia? - Answers lethargy, confusion,
vomiting
Advanced clinical manifestations of azotemia:
Impaired ____
_____ disturbances
______ imbalance
neuropathy - Answers vitamin d activation
electrolyte
acid-base
Salt wasting leads to impaired tubular absorption of _____ - Answers sodium
What are clinical manifestations of impaired acid-base balance? - Answers fluid overload
, hyperkalemia
hyponatremia
metabolic acidosis
hyperphosphatemia
hypocalcemia
Phosphate retention and low calcitriol lead to ____ - Answers hypocalcemia
Low calcium triggers ____ release leading to ____ and calcium being taken from the bone -
Answers PTH, hyperparathyroidism
Chronic PTH elevation leads to... - Answers bone demineralization
renal osteodystrophy
Hematologic effects of CKD include... - Answers hemolysis
bone marrow suppression
coagulopathy
What are cardiovascular clinical manifestations of CKD? - Answers tachycardia
pallor
dyspnea
palpitations
Cardiovascular alterations of CKD include increased _____ and ____, and decreased _____ -
Answers vascular volume, RAAS
vasodilator prostaglandins
Heart disease in CKD develops from... - Answers ECF overload, anemia, shunts, hypertension
Gastrointestinal alterations in CKD include high ____ and ____ - Answers ammonia, gastric acid
Neuromuscular alterations in CKD include... - Answers peripheral neuropathy
CKD impairs _____ response - Answers immune
What are disorders of skin integrity in CKD? - Answers pallor
xerosis