Board Certified Infectious Diseases
Pharmacist (BCIDP) Practice Exam Verified
Questions, Correct Answers, and Detailed
Explanations for Science Students||Already
Graded A+
1. Which organism is the most common cause of community-
acquired pneumonia in adults?
A. Haemophilus influenzae
B. Staphylococcus aureus
C. Streptococcus pneumoniae
D. Legionella pneumophila
Answer: C
Streptococcus pneumoniae remains the most common cause of CAP
despite vaccination efforts.
2. Which antibiotic exhibits concentration-dependent killing?
A. Vancomycin
B. Linezolid
C. Gentamicin
D. Ceftriaxone
Answer: C
Aminoglycosides demonstrate concentration-dependent killing and
post-antibiotic effect.
3. What is the preferred empiric therapy for suspected neutropenic
fever?
,A. Ceftriaxone
B. Vancomycin alone
C. Piperacillin-tazobactam
D. Azithromycin
Answer: C
Broad-spectrum antipseudomonal beta-lactams are first-line for
neutropenic fever.
4. Which resistance mechanism is associated with MRSA?
A. Efflux pump overexpression
B. Beta-lactamase production
C. Altered penicillin-binding protein (PBP2a)
D. Porin loss
Answer: C
MRSA resistance is due to mecA-mediated altered PBP (PBP2a).
5. What is the drug of choice for Listeria monocytogenes
meningitis?
A. Ceftriaxone
B. Ampicillin
C. Meropenem
D. Vancomycin
Answer: B
Ampicillin is the treatment of choice for Listeria infections.
6. Which antifungal is first-line for invasive candidiasis in critically ill
patients?
,A. Fluconazole
B. Voriconazole
C. Amphotericin B
D. Echinocandin
Answer: D
Echinocandins are preferred initially due to broad activity and safety.
7. What laboratory parameter best correlates with vancomycin
efficacy?
A. Peak concentration
B. Trough concentration
C. AUC/MIC
D. Half-life
Answer: C
AUC/MIC ≥400 is associated with clinical efficacy.
8. Which virus is most commonly associated with post-transplant
lymphoproliferative disorder?
A. CMV
B. HSV
C. Epstein-Barr virus
D. HHV-6
Answer: C
EBV-driven B-cell proliferation causes PTLD.
9. What is the treatment of choice for Clostridioides difficile severe
infection?
, A. Metronidazole
B. Oral vancomycin
C. Fidaxomicin IV
D. Rifaximin
Answer: B
Oral vancomycin is recommended for severe CDI.
10. Which pathogen is intrinsically resistant to vancomycin?
A. MRSA
B. Streptococcus pyogenes
C. Enterococcus faecium (VRE)
D. Streptococcus agalactiae
Answer: C
Vancomycin resistance is intrinsic or acquired in Enterococcus
species.
11. Which antibiotic is associated with QT prolongation?
A. Amoxicillin
B. Azithromycin
C. Cefazolin
D. Daptomycin
Answer: B
Macrolides may prolong the QT interval.
12. Which antifungal has activity against Mucorales?
A. Voriconazole
B. Fluconazole
Pharmacist (BCIDP) Practice Exam Verified
Questions, Correct Answers, and Detailed
Explanations for Science Students||Already
Graded A+
1. Which organism is the most common cause of community-
acquired pneumonia in adults?
A. Haemophilus influenzae
B. Staphylococcus aureus
C. Streptococcus pneumoniae
D. Legionella pneumophila
Answer: C
Streptococcus pneumoniae remains the most common cause of CAP
despite vaccination efforts.
2. Which antibiotic exhibits concentration-dependent killing?
A. Vancomycin
B. Linezolid
C. Gentamicin
D. Ceftriaxone
Answer: C
Aminoglycosides demonstrate concentration-dependent killing and
post-antibiotic effect.
3. What is the preferred empiric therapy for suspected neutropenic
fever?
,A. Ceftriaxone
B. Vancomycin alone
C. Piperacillin-tazobactam
D. Azithromycin
Answer: C
Broad-spectrum antipseudomonal beta-lactams are first-line for
neutropenic fever.
4. Which resistance mechanism is associated with MRSA?
A. Efflux pump overexpression
B. Beta-lactamase production
C. Altered penicillin-binding protein (PBP2a)
D. Porin loss
Answer: C
MRSA resistance is due to mecA-mediated altered PBP (PBP2a).
5. What is the drug of choice for Listeria monocytogenes
meningitis?
A. Ceftriaxone
B. Ampicillin
C. Meropenem
D. Vancomycin
Answer: B
Ampicillin is the treatment of choice for Listeria infections.
6. Which antifungal is first-line for invasive candidiasis in critically ill
patients?
,A. Fluconazole
B. Voriconazole
C. Amphotericin B
D. Echinocandin
Answer: D
Echinocandins are preferred initially due to broad activity and safety.
7. What laboratory parameter best correlates with vancomycin
efficacy?
A. Peak concentration
B. Trough concentration
C. AUC/MIC
D. Half-life
Answer: C
AUC/MIC ≥400 is associated with clinical efficacy.
8. Which virus is most commonly associated with post-transplant
lymphoproliferative disorder?
A. CMV
B. HSV
C. Epstein-Barr virus
D. HHV-6
Answer: C
EBV-driven B-cell proliferation causes PTLD.
9. What is the treatment of choice for Clostridioides difficile severe
infection?
, A. Metronidazole
B. Oral vancomycin
C. Fidaxomicin IV
D. Rifaximin
Answer: B
Oral vancomycin is recommended for severe CDI.
10. Which pathogen is intrinsically resistant to vancomycin?
A. MRSA
B. Streptococcus pyogenes
C. Enterococcus faecium (VRE)
D. Streptococcus agalactiae
Answer: C
Vancomycin resistance is intrinsic or acquired in Enterococcus
species.
11. Which antibiotic is associated with QT prolongation?
A. Amoxicillin
B. Azithromycin
C. Cefazolin
D. Daptomycin
Answer: B
Macrolides may prolong the QT interval.
12. Which antifungal has activity against Mucorales?
A. Voriconazole
B. Fluconazole
