NURS 615 PHARM EXAM [4] QUESTIONS WITH
100% COMPLETE SOLUTIONS| LATEST
UPDATE
miralax - correct answer-this medication can be given concurrently for children to treat
constipation along with potential need for behavior modification as appropriate
stimulant laxatives - correct answer-bowel dependency may occur if used long term with
these medications
phenothiazine antiemetics - correct answer-block dopamine receptors in the chemo
trigger zone
-promethazine
-prochlorperazine
These medications antagonize dopaminergic D2 receptors in various pathways to the
CNS. The D2, or dopamine blockade, results in antipsychotic, antiemetic, and other
effects.
docusate sodium - correct answer-incorporates water and lipids into stool and reduce
surface tension
proton pump inhibitors - correct answer-these work irreversibly by combing the H+-K+-
ATPase proton pump which. This reduced blood flow to stomach and decreases pepsin
secretin and lipase serum
(suppresses gastric acid secretion by inhibiting the parietal cell)
ondansetron (zofran) - correct answer-elective 5-HT3-receptor antagonist, blocking
serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor
trigger zone
misoprostol (cytotec) - correct answer-contrainidicated in pregnancy or those in child
bearing age as they cause a 70% incidence of abortion
, loop diuretics - correct answer-can lead to the excretion of up to 20 to 25 percent of
filtered sodium [1,10]. They act in the medullary and cortical aspects of the thick
ascending limb, including the macula densa cells in the early distal tubule.
appear to compete for the chloride site on this carrier, thereby diminishing net
reabsorption
loop diuretics - correct answer-furosemide, bumetadine, torsemide
thiazide diuretics - correct answer-primarily inhibit sodium transport in the distal tubule
the connecting segment at the end of the distal tubule and possibly the cortical
collecting tubule
thiazide diuretics - correct answer-hydrochlorthiazide
potassium sparing diuretics - correct answer-act in the principal cells in the cortical
collecting tubule
decrease the number of open sodium channels in the principal cells by two different
mechanisms
-Amiloride and triamterene
-spironolactone
acetazolamide - correct answer-inhibits the activity of carbonic anhydrase, which plays
an important role in proximal bicarbonate, sodium, and chloride reabsorption. As a
result, this agent produces both NaCl and NaHCO3 loss
mannitol - correct answer-nonreabsorbable sugar alcohol that acts as an osmotic
diuretic, inhibiting sodium and water reabsorption in the proximal tubule and more
importantly the loop of Henle
hydrochlorothiazide - correct answer-for tx of mild htn started at a low dose of 12.5 mg
and increased to 25 g
furosemide - correct answer-for tx of moderate to severe with dose from 20mg to 40 mg
mast cell stabilizers - correct answer-cramolyn, nedocromil
alter function of CL channel
inhibits cough, inhibits mast cell and eosiniphil response to antigens
100% COMPLETE SOLUTIONS| LATEST
UPDATE
miralax - correct answer-this medication can be given concurrently for children to treat
constipation along with potential need for behavior modification as appropriate
stimulant laxatives - correct answer-bowel dependency may occur if used long term with
these medications
phenothiazine antiemetics - correct answer-block dopamine receptors in the chemo
trigger zone
-promethazine
-prochlorperazine
These medications antagonize dopaminergic D2 receptors in various pathways to the
CNS. The D2, or dopamine blockade, results in antipsychotic, antiemetic, and other
effects.
docusate sodium - correct answer-incorporates water and lipids into stool and reduce
surface tension
proton pump inhibitors - correct answer-these work irreversibly by combing the H+-K+-
ATPase proton pump which. This reduced blood flow to stomach and decreases pepsin
secretin and lipase serum
(suppresses gastric acid secretion by inhibiting the parietal cell)
ondansetron (zofran) - correct answer-elective 5-HT3-receptor antagonist, blocking
serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor
trigger zone
misoprostol (cytotec) - correct answer-contrainidicated in pregnancy or those in child
bearing age as they cause a 70% incidence of abortion
, loop diuretics - correct answer-can lead to the excretion of up to 20 to 25 percent of
filtered sodium [1,10]. They act in the medullary and cortical aspects of the thick
ascending limb, including the macula densa cells in the early distal tubule.
appear to compete for the chloride site on this carrier, thereby diminishing net
reabsorption
loop diuretics - correct answer-furosemide, bumetadine, torsemide
thiazide diuretics - correct answer-primarily inhibit sodium transport in the distal tubule
the connecting segment at the end of the distal tubule and possibly the cortical
collecting tubule
thiazide diuretics - correct answer-hydrochlorthiazide
potassium sparing diuretics - correct answer-act in the principal cells in the cortical
collecting tubule
decrease the number of open sodium channels in the principal cells by two different
mechanisms
-Amiloride and triamterene
-spironolactone
acetazolamide - correct answer-inhibits the activity of carbonic anhydrase, which plays
an important role in proximal bicarbonate, sodium, and chloride reabsorption. As a
result, this agent produces both NaCl and NaHCO3 loss
mannitol - correct answer-nonreabsorbable sugar alcohol that acts as an osmotic
diuretic, inhibiting sodium and water reabsorption in the proximal tubule and more
importantly the loop of Henle
hydrochlorothiazide - correct answer-for tx of mild htn started at a low dose of 12.5 mg
and increased to 25 g
furosemide - correct answer-for tx of moderate to severe with dose from 20mg to 40 mg
mast cell stabilizers - correct answer-cramolyn, nedocromil
alter function of CL channel
inhibits cough, inhibits mast cell and eosiniphil response to antigens
