A. Sweating.
B. Bradycardia.
C. Confusion.
D. Weakness.
2. The thiazolidinediones should not be used concomitantly with a(n):
A. Angiotensin-converting enzyme inhibitor.
B. Nitrate.
C. Calcium channel antagonist.
D. Beta-adrenergic antagonist.
3. Consequences of hyperinsulinemia include all of the following except:
A. Altered vessel membrane permeability.
B. Less response to angiotensin II.
C. Enhanced renal tubule reabsorption of sodium.
D. Endothelial dysfunction.
4. The mechanism of action of sulfonylureas is as a(n):
A. Product that enhances insulin release.
B. Regulator of insulin receptor site activity.
C. Agent that can reduce hepatic glucose production.
D. Facilitator of renal glucose excretion.
5. Which of the following is consistent with the diagnosis of diabetes mellitus?
A. Fasting plasma glucose=100 mg/dL (5.6 mmol/L) to 125 mg/dL (6.9 mmol/L)
B. Hemoglobin A1C =6.5%
C. Plasma glucose=140 to 199 mg/dL (7.8 to 11.0 mmol/L) on the 75-g
oral glucose tolerance test
D. Random plasma glucose =125 mg/dL without classic diabetes mellitus
symptoms
6. SGLT2 inhibitors exert their clinical effect by:
A. Increasing glucose utilization in the muscle.
B. Reducing insulin resistance in the skeletal muscle and adipose tissue.
C. Delaying carbohydrate absorption.
D. Increasing glucose excretion in the urine.
7. Delayed gastric emptying is noted with the use of:
A. Exenatide (Byetta®).
B. Pioglitazone (Actos®).
C. Acarbose (Precose®).
D. Glyburide (Micronase®).
8. In a healthy person, basal insulin accounts for what percentage of the body's total
daily physiologic insulin secretion?
A. 10%
B. 25%
C. 50%
D. 75%
9. Which of the following best describes a component of sitagliptin’s (Januvia®)
mechanism of action?
A. Agent that increases hepatic glucose utilization
B. Increases insulin release by slowing inactivation of incretin hormones
C. Facilitator of renal glucose excretion
D. Enhancer of insulin receptor site activity