Questions And Answers Verified 100% Correct
What is the most common clearance test used to measure the glomerular filtration
rate? (GFR) - ANSWER -Creatinine
A creatinine clearance test is performed. The 24-hour urine volume is 770 mL;
serum creatinine is 2.0 mg/dL and urine creatinine is 240 mg/dL. What is the
clearance, assuming average body surface area? - ANSWER -GFR = ([UCr x
V]/SCr)/1440
64 mL/minute = [(240 x 770)/2]/1440
(1440 minutes in 24 hours)
Which disease state is associated with an elevation of serum uric acid? -
ANSWER -Gout
Which reagent is employed in the alkaline oxidation of uric acid? - ANSWER -
Phosphotungstic acid
What does the uricase method for uric acid depend on? - ANSWER -UV
absorption at 290 nm before/after treatment with uricase
Which one of the following analytes is used as a prognostic indicator for liver
failure? - ANSWER -Ammonia
Which disaccharide is composed of two glucose molecules? - ANSWER -Maltose
What term is used to describe the process of glycogen degradation? - ANSWER -
Glycogenolysis
What is the renal threshold for glucose? - ANSWER -160-180 mg/dL
Which hormone is produced by the beta cells of the islets of Langerhans? -
ANSWER -Insulin
, Which one of the following hormones is considered a glucocorticoid? - ANSWER
-Cortisol
A 40-year-old male has a randome glucose of 470 mg/dL. This lab finding is
consistent with which one of the following clinical conditions? - ANSWER -
Diabetes mellitus
Which one of the following diseases is associated with hypoglycemia? -
ANSWER -von Gierke's disease
What is the specimen of choice for glucose determinations? - ANSWER -
Fluorinated plasma
What is the most frequently employed automated method for glucose? - ANSWER
-Coupled enzyme system consisting of glucose oxidase and peroxidase.
Contamination of the glucose reagent with catalase is a problem with which
glucose method? - ANSWER -Glucose oxidase
What is the hexokinase methodology for glucose determination based on? -
ANSWER -Reduced coenzyme read at 340 nm
What is the normal fasting blood glucose (FBS) reference range for adults? -
ANSWER -70-110 mg/dL
Prenatal patients with borderline blood glucose levels are further evaluated by
which test? - ANSWER -3-hour glucose tolerance test (GTT)
Which test gives a 2-3 month picture of a diabetic's glucose levels? - ANSWER -
Hemoglobin A1C
What does the presence of urinary ketones MOST likely indicate? - ANSWER -
Storage lipids are being used as the primary energy source.
, Which one of the following tests is used to differentiate between inappropriate
exogenous insulin administration and endogenous insulin production? - ANSWER
-C-peptide
The "port wine" color of some urines can be attributed to which of the following?
- ANSWER -Porphyrins
p-dimethylaminobenzaldehyde is a constituent of which reagent? - ANSWER -
Ehrlich
Both porphobilinogen and urobilinogen form a red-colored compound with
Ehrlich's reagent. How can they be differentiated? - ANSWER -Urobilinogen is
soluble in chloroform
Prehepatic bilirubin has which of the following for a carrier? - ANSWER -
Albumin
Direct-reacting bilirubin is also known as what substance? - ANSWER -Bilirubin
diglucaronide
An increase in indirect-reacting bilirubin is suggestive of which condition? -
ANSWER -Hemoglobin breakdown
Bilirubin is converted in the intestine to which of the following substances? -
ANSWER -Urobilinogen
Which of the following will interfere with the Evelyn Malloy method for
bilirubin? - ANSWER -Hemolysis
Which precaution should be followed in regard to specimen handling instructions
for bilirubin determinations? - ANSWER -Protect from light
Which one of the following definitions best describes an enzyme? - ANSWER -
Biologic catalyst