NR546 / NR 546 FINAL EXAM 120 + QUESTIONS AND CORRECT ANSWERS LATEST STUDY GUIDE 2026 .

NR546 / NR 546 FINAL EXAM 120 + QUESTIONS AND CORRECT ANSWERS LATEST STUDY GUIDE 2026 . 2 / 13 1. First line treatment for depression correct answer SSRIs 2. Common side effect of SSRIs correct answer sexualdysfunction 3. rapid cycling bipolar disorder correct answer Minimum of 4 episodes a year 4. Goal of antidepressant therapy correct answer complete remission ofsymptoms 5. Serotonin GI effects correct answer Due to the fact that 90% of 5HT receptors are located in GI tract 6. best tolerated SSRI correct answer Escitalopram (Lexapro) also hasfewest CYP interactions 7. Lithium levels correct answer Can be increased by NSAIDS and ACE inhibitors Can be decreased by catteine and mania Unattected by amiloride, furosemide, and sulindac 8. Lithium purpose correct answer Ettective treatment for manic episodes, to prevent reoccurrence and to a lower degree is ettective in depressive episodes 9. Lamotrigine correct answer Well tolerated except for the propensity to cause a rash 10. Monoamines correct answer dopamine, norepinephrine, serotonin 11. Lamotrigine correct answer Is a mood stabilizer 12. Lithium correct answer Well established to prevent suicide in clients with mood disorders 13. Lithium correct answer Has a narrow therapeutic window and requires law draws 14. 1st line treatment for OCD correct answer SSRIs are first line. Benzodiazepines are not!!! 15. Primary action of hallucinogenic drugs such as LSD,mescaline, psilocybin, and MDMA correct answer Agonismof 5HT2Areceptors Hallucinogens may have additional actions at other serotonin receptors (particularly 5HT1A and 5HT2C) and at other neurotransmitter systems, and MDMA in particular also blocksthe serotonin transporter (SERT) 16. Controls appetite correct answer hypothalamus serves as the brain center that controls appetite by utilizing a complex set of circuits and regulators. One formulation of how the hypothalamus does this is the notion that there is a major appetite stimulating pathway whose actions are mediated by two peptides (neuropeptide Y and agouti-related protein) 17. Phentermine correct answer Acts like amphetamine, blocking both the dopamine transporter (DAT) and the norepinephrine transporter (NET) and, at high doses, the vesicular monoamine transporter (VMAT) 18. Buprenorphine correct answer Is also approved for <18 year olds 19. Disulfiram caution correct answer Alcohol reaction may occur within two weeks of alcohol ingestion 3 / 13 20. Methadone correct answer Is a full mu-receptor agonist with a long half-life, which can prevent withdrawal symptoms for 24 hours and provide steady control of cravings throughout the day. In addition to its opioid receptor activity, it is also an antagonist of the N-methyl-D-aspartate (NMDA) receptor. 21. Hallucinogenic intoxication correct answer pupillary dilation, tachycardia, sweating, palpitations, blurred vision, tremors, incoordination Can be perceived as a panic attack and often called a bad trip. Can experience an acute state of confusion (delirium) where the abuser is disoriented and agitated. 22. Disulfiram correct answer Irreversibly inhibits aldehyde dehydrogenase resulting in build of toxic levels of acetaldehyde Acamprosate reduces glutamate release associated with alcohol withdrawal, naltrexone blocks the enjoyment of heavy drinking through its action on reward circuitry. 23. sedative-hypnotics correct answer Act at GABA A receptor sitesin reward circuits 24. Impulsive Disorders correct answer Focused on reward and associated with Mesolimbic pathway 25. The Tuberomammillary nucleus (TMN) correc