Neurology IM EORE (Internal Medicine) | 45 Questions | Stroke, Seizures, HA, MS, Neuropathies | 2025

This comprehensive study guide includes 45 expert-verified flashcard-style Q&A items tailored for the Neurology section of the Internal Medicine End-of-Rotation Exam (IM EORE), aligned with the 2025 academic curriculum. It serves as a focused, high-yield resource for rapid review of core neurologic conditions, diagnostics, and management—perfect for students preparing for clinical rotations, board exams, or emergency settings. The document covers a full spectrum of seizure types: Grand-mal (tonic-clonic), partial, absence (petit mal), and status epilepticus, including signs such as tongue biting, Jacksonian march, and postictal phase. Workup includes EEG, labs, CT/MRI, and treatment escalation from benzodiazepines to phenobarbital. Headaches are classified with precision: Migraines (unilateral, aura, triptans), Tension headaches (band-like pressure, NSAIDs), and Cluster headaches (retro-orbital, male predominance, relieved with oxygen). Extensive attention is given to cerebrovascular events: TIAs and strokes (ischemic and hemorrhagic) by vascular territory (MCA, ACA, PCA) with characteristic symptoms, timing of tPA administration, and CT-first approach. Subarachnoid hemorrhage (SAH) is included with "worst headache of life", imaging, and risk factors like hypertension and smoking. Movement and neuromuscular disorders include: Parkinson’s disease, essential tremor, and Huntington’s disease (chorea, psychiatric changes). Multiple sclerosis (MS) diagnosis with MRI + oligoclonal bands, and treatment with interferon-β and steroids. Myasthenia gravis (fatigable weakness, ptosis, ACh receptor antibodies) with pyridostigmine and thymectomy. Neuropathic and degenerative disorders are well summarized: Peripheral neuropathy (most often diabetic) and complex regional pain syndrome (CRPS). Dementia (Alzheimer's, Lewy Body) vs delirium, with clear comparisons and pharmacologic treatment options like donepezil and memantine. Infectious and inflammatory neurologic disorders include: Meningitis (Kernig’s/Brudzinski, empiric vanco + ceftriaxone) Encephalitis (HSV, PCR, IV acyclovir) Guillain-Barré syndrome (ascending paralysis, IVIG, plasma exchange) This document is ideal for: PA students preparing for the IM EORE Neurology component Medical students (MD/DO) in clinical rotations or studying for Step 2/COMLEX Nurse Practitioner (NP) and nursing students covering neurologic systems Any student preparing for PANCE, USMLE, or clinical assessments Its highly organized format allows for quick lookups and fast-paced revision, combining clinical facts with relevant diagnostics and treatment pathways. Keywords: seizures, epilepsy, status epilepticus, migraine, cluster headache, tension headache, stroke, TIA, tPA, MS, MRI, Parkinson’s, Huntington’s, myasthenia gravis, neuropathy, CRPS, Guillain-Barré, SAH, aneurysm, meningitis, encephalitis, Bell palsy, cerebral aneurysm, dementia, delirium, anticonvulsants, neurology EORE prep