Which definition best describes a lead compound?
Give this one a try later!
The first compound discovered to have the desired activity.
Which type of response curve would you look at if you wanted to know the exact
response predicted in a controlled system at a specified drug concentration?
Give this one a try later!
Graded concentration response
,The transition between which two phases of translational research involves switching
from controlled settings to real-world settings?
Give this one a try later!
T2-T3
What government agency regulates phase I clinical trails in the US?
Give this one a try later!
FDA
In which type of clinical trial is every pt guaranteed to receive active drug?
Give this one a try later!
Cross-over trail
A pt was given a dose of isoniazid and the plasma concentration was 2 mg/L. One
hour later their plasma concentration was 1.75 mg/L. Is that person most likely a fast or
slow acetylator?
Give this one a try later!
, Slow
Overnight contact lenses are considered class ___ medical devices?
Give this one a try later!
Class III
Once insulin reaches the pancreas, how long do you expect it to take before a
response can be measured?
Give this one a try later!
Minutes
Which of the following requires direct action by a patient (or guardian) before they
can be enrolled in a phase I clinical trial?
Give this one a try later!
Informed consent
Would a pt with overactive VKORC1 need a higher, lower, or equal dose of warfarin to
someone with normal VKORC1?
Give this one a try later!
The first compound discovered to have the desired activity.
Which type of response curve would you look at if you wanted to know the exact
response predicted in a controlled system at a specified drug concentration?
Give this one a try later!
Graded concentration response
,The transition between which two phases of translational research involves switching
from controlled settings to real-world settings?
Give this one a try later!
T2-T3
What government agency regulates phase I clinical trails in the US?
Give this one a try later!
FDA
In which type of clinical trial is every pt guaranteed to receive active drug?
Give this one a try later!
Cross-over trail
A pt was given a dose of isoniazid and the plasma concentration was 2 mg/L. One
hour later their plasma concentration was 1.75 mg/L. Is that person most likely a fast or
slow acetylator?
Give this one a try later!
, Slow
Overnight contact lenses are considered class ___ medical devices?
Give this one a try later!
Class III
Once insulin reaches the pancreas, how long do you expect it to take before a
response can be measured?
Give this one a try later!
Minutes
Which of the following requires direct action by a patient (or guardian) before they
can be enrolled in a phase I clinical trial?
Give this one a try later!
Informed consent
Would a pt with overactive VKORC1 need a higher, lower, or equal dose of warfarin to
someone with normal VKORC1?
