In which type of clinical trial is a MTD most likely to be determined?
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Phase 1
Which of the following requires direct action by a patient (or their guardian) before
they can be enrolled in a phase I clinical trial?
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informed consent
Which branch of pharmacology studies the effect of the body on drugs?
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Pharmacokinetics
Which branch of pharmacology studies the desired effect of drugs on the body,
usually at the molecular level?
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Pharmacodynamics
Naloxone binds to the opioid receptor, preventing opioids from binding, therefore
preventing an effect. In this situation, naloxone is a(n) ______ and the opioid is a(n) ______.
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antagonist; agonist
Which of the following (choose all that are correct) could happen if a single SNP
exists?
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A truncated drug metabolizing enzyme
A leucine changed to a phenylalanine in a receptor that prevents drug
binding
There would be no observable change in protein sequence or structure
, Genetics can influence which of the following (choose none, some, or all).
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Pharmacokinetics
Pharmacodynamics
In which type of clinical trial is every patient guaranteed to receive the new drug that
is being tested?
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Cross-over trial
A tuberculosis patient is not responding to isoniazid treatment. The physician takes a
DNA sample from the patient and sends it for testing. What gene is she likely having
genotyped?
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N-acetyl transferase
What government agency regulates phase I clinical trials in the United States?
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Give this one a try later!
Phase 1
Which of the following requires direct action by a patient (or their guardian) before
they can be enrolled in a phase I clinical trial?
Give this one a try later!
informed consent
Which branch of pharmacology studies the effect of the body on drugs?
,Give this one a try later!
Pharmacokinetics
Which branch of pharmacology studies the desired effect of drugs on the body,
usually at the molecular level?
Give this one a try later!
Pharmacodynamics
Naloxone binds to the opioid receptor, preventing opioids from binding, therefore
preventing an effect. In this situation, naloxone is a(n) ______ and the opioid is a(n) ______.
Give this one a try later!
antagonist; agonist
Which of the following (choose all that are correct) could happen if a single SNP
exists?
Give this one a try later!
A truncated drug metabolizing enzyme
A leucine changed to a phenylalanine in a receptor that prevents drug
binding
There would be no observable change in protein sequence or structure
, Genetics can influence which of the following (choose none, some, or all).
Give this one a try later!
Pharmacokinetics
Pharmacodynamics
In which type of clinical trial is every patient guaranteed to receive the new drug that
is being tested?
Give this one a try later!
Cross-over trial
A tuberculosis patient is not responding to isoniazid treatment. The physician takes a
DNA sample from the patient and sends it for testing. What gene is she likely having
genotyped?
Give this one a try later!
N-acetyl transferase
What government agency regulates phase I clinical trials in the United States?
Give this one a try later!
