N154 at UCI (MOLECULAR NEUROBIOLOGY) -
Midterm 1 Prep with Correct Answers
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Terms in this set (19)
1.1 Neurotransmitter
Neurons are connected but not physically. They have
on and off connection. They are not always
Synapses: connected. 3 important components of a neuron
include 1) presyanptic neuron 2) synaptic cleft 3)
postsynaptic membrane receptor molecule
1)Electrical communication: Action potential
produced. We need a particular protein.
Neuron Communication
2) Chemical communication: Neurotransmitter binding
to receptor.
, Neurons have negative membrane potential. Outside
the cell, Na+ concentration is higher. K+ concentration
is also higher inside the cell. The concentration
gradient of ions such as Na+ and K+ make potential
difference inside and outside a cell. Due to this
concentration gradient, ions want to move down their
concentration gradient. However, this electrochemical
gradient is maintained by Na+/K+ pump. Na+/K+ pump
How is electrochemical needs ATP to operate and maintain electrochemical
gradient maintained? gradient.
What is the significance of Neurons use electrochemical gradient when Na+
electrochemical graident channel opens. Na+ influx reduces negative
produced by Na+/K+ membrane potential and depolarizes the cell. This is
pump? the fundamental mechanism for exciting neuron.
At rest, Na+ channel gate is closed. When AP is
generated, voltage is sensed through voltage sensor
and because of the electrochemical gradient Na+
moves down their concentration gradient and
depolarize the cell.
Generation of action potential requires
electrochemical gradient which is established by
Na+/K+ pump.
Why Na+/K+ pump is It is required to maintain electrochemical gradient
important?
What is the significance of It is required to excite neurons and generate action
electrochemical gradient? potential or synaptic potentiation.
Midterm 1 Prep with Correct Answers
Save
Terms in this set (19)
1.1 Neurotransmitter
Neurons are connected but not physically. They have
on and off connection. They are not always
Synapses: connected. 3 important components of a neuron
include 1) presyanptic neuron 2) synaptic cleft 3)
postsynaptic membrane receptor molecule
1)Electrical communication: Action potential
produced. We need a particular protein.
Neuron Communication
2) Chemical communication: Neurotransmitter binding
to receptor.
, Neurons have negative membrane potential. Outside
the cell, Na+ concentration is higher. K+ concentration
is also higher inside the cell. The concentration
gradient of ions such as Na+ and K+ make potential
difference inside and outside a cell. Due to this
concentration gradient, ions want to move down their
concentration gradient. However, this electrochemical
gradient is maintained by Na+/K+ pump. Na+/K+ pump
How is electrochemical needs ATP to operate and maintain electrochemical
gradient maintained? gradient.
What is the significance of Neurons use electrochemical gradient when Na+
electrochemical graident channel opens. Na+ influx reduces negative
produced by Na+/K+ membrane potential and depolarizes the cell. This is
pump? the fundamental mechanism for exciting neuron.
At rest, Na+ channel gate is closed. When AP is
generated, voltage is sensed through voltage sensor
and because of the electrochemical gradient Na+
moves down their concentration gradient and
depolarize the cell.
Generation of action potential requires
electrochemical gradient which is established by
Na+/K+ pump.
Why Na+/K+ pump is It is required to maintain electrochemical gradient
important?
What is the significance of It is required to excite neurons and generate action
electrochemical gradient? potential or synaptic potentiation.
