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NCLEX-RN Comprehensive Study Guide & Practice Questions: 500+ Exam Prep Scenarios with Detailed Rationales

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Ace your nursing exams with this all-in-one study guide featuring over 500 NCLEX-style practice questions and detailed rationales. Covering a wide range of topics—from pediatric care and pharmacology to postoperative management, mental health, and clinical decision-making—this resource is designed to help nursing students and new graduates build confidence, reinforce critical thinking, and master essential nursing concepts. Each question includes clear explanations, helping you understand not just the correct answer, but the reasoning behind it. Ideal for NCLEX-RN preparation, classroom review, or clinical practice reinforcement.

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Uploaded on
December 15, 2025
Number of pages
174
Written in
2025/2026
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Exam (elaborations)
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Questions & answers

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A nurse in a provider's office is reviewing pediculosis capitis
management and prevention strategies with the parent of a school-age
child. Which of the following strategies should the nurse include?
Select all that apply. - ANSWER--Store the child's clothing in a separate
cubicle when at school.


Boil brushes and combs in water for 10 min.


Dry bed linens and clothing in a hot dryer for at least 20 min.


A nurse is monitoring a client who is 12 hr postoperative following a
cholecystectomy and received morphine 30 min ago for pain. The nurse
should identify which of the following findings as an adverse effect of
the medication? - ANSWER--Respiratory rate 10/min




A respiratory rate of 10/min indicates respiratory depression, which is
an adverse effect of morphine.

,A nurse is reviewing laboratory reports for a client who has an
Escherichia coli infection and is receiving gentamicin. Which of the
following results should the nurse report to the provider before
administering the next dose? - ANSWER--Creatinine 2.5 mg/dL (0.5 to
1.1 mg/dL)




The nurse should report the creatinine level of 2.5 mg/dL to the
provider prior to administering any further doses of the medication
because gentamicin is nephrotoxic and can result in acute tubular
necrosis. A creatinine level above the expected reference range is an
indication of kidney impairment.


A nurse is caring for an older adult client who is experiencing difficulty
sleeping. Which of the following actions should the nurse take? -
ANSWER--Offer the client a snack of whole grain crackers before
bedtime.




The nurse should provide the client a light carbohydrate snack, such
as whole grain crackers, before bedtime.

,A nurse is reinforcing teaching with a client who is to self-administer
epoetin alfa. Which of the following instructions should the nurse
include? - ANSWER--Administer the medication subcutaneously.




The nurse should instruct the client to self-administer epoetin alfa via
the subcutaneous route.


A licensed practical nurse (LPN) is reviewing client assignments for the
upcoming shift. Which of the following clients should the LPN ask the
charge nurse to reassign to a registered nurse (RN)? - ANSWER--A client
who has a new colostomy and requires the development of a teaching
plan




Developing a client teaching plan is not within the scope of practice
for an LPN. The nurse should contact the nursing supervisor to inform
them of the client's need for a teaching plan regarding the new
colostomy and request that this client be reassigned to an RN. The
scope of practice of an LPN does allow the nurse to reinforce teaching
once the plan has been established.

, A nurse is collecting data from a client who has type 2 diabetes mellitus
and is concerned about weight gain during pregnancy. Which of the
following responses should the nurse make? - ANSWER--"Your weight
gain should be the same as for someone without diabetes."




A client who is pregnant and has diabetes mellitus should gain the
same amount of weight as a client without diabetes mellitus.


A nurse is caring for a client who has Alzheimer's disease. Which of the
following actions should the nurse take? - ANSWER--encourage the
client to reminisce about the past.




The client who has Alzheimer's disease has progressive loss of short-
term memory and might not be able to recall recent happenings and
events. This can lead to increased frustration. However, remote
memory remains in place for a longer period of time and can elicit
feelings of happiness.
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