The most recent estimates indicate that the human genome has a total of ~58,000 genes,
approximately subdivided into:
~30,000 protein-coding genes, ~28,000 pseudogenes
~20,000 protein-coding genes, ~10,000 lncRNAs, ~8000 sncRNAs, ~20,000 pseudogenes
~58,000 protein-coding genes
~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes -
Answers ~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000
pseudogenes
Sequencing the human genome provided much information on elements that scientists knew
existed but had little information on the structure of, such as (select all that apply):
Origins of replication
Promoter
Protein binding sites
Enhancers - Answers Origins of replication
Promoter
Protein binding sites
Enhancers
The properties of the human nuclear and mitochondrial genomes are very different. In particular:
The mitochondrial genome is largely composed of highly conserved sequences, while the
nuclear genome is largely composed of poorly conserved sequences
The nuclear genome is largely composed of highly conserved sequences, while the
mitochondrial genome is largely composed of poorly conserved sequences - Answers The
mitochondrial genome is largely composed of highly conserved sequences, while the nuclear
genome is largely composed of poorly conserved sequences
Segmental duplications (select all that apply):
, Can create chimeric genes
Have been associated with disorders like autism
Have helped shape the human genome
Are defined as duplications of > 1 kb with > 90% identity - Answers Can create chimeric genes
Have been associated with disorders like autism
Have helped shape the human genome
Are defined as duplications of > 1 kb with > 90% identity
Long non-coding RNAs (select all that apply):
Can be involved in transcriptional control
Can be involved in post-transcriptional processing
Are likely involved in other processes that we are not aware of
Can be involved in chromatin remodelling - Answers Can be involved in transcriptional control
Can be involved in post-transcriptional processing
Are likely involved in other processes that we are not aware of
Can be involved in chromatin remodelling
A current controversy in the field of epigenetics is whether:
Epigenetic markings actually exist
Humans are the only species that have epigenetic gene regulation
Epigenetic marks are a cause or a consequence of disease
Epigenetic markings are caused by methylation alone - Answers Epigenetic marks are a cause
or a consequence of disease
Non-coding RNAs are not conserved across species. This makes it difficult to: