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MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026

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MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026 The most recent estimates indicate that the human genome has a total of ~58,000 genes, approximately subdivided into: ~30,000 protein-coding genes, ~28,000 pseudogenes ~20,000 protein-coding genes, ~10,000 lncRNAs, ~8000 sncRNAs, ~20,000 pseudogenes ~58,000 protein-coding genes ~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes - Answers ~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes Sequencing the human genome provided much information on elements that scientists knew existed but had little information on the structure of, such as (select all that apply): Origins of replication Promoter Protein binding sites Enhancers - Answers Origins of replication Promoter Protein binding sites Enhancers The properties of the human nuclear and mitochondrial genomes are very different. In particular: The mitochondrial genome is largely composed of highly conserved sequences, while the nuclear genome is largely composed of poorly conserved sequences The nuclear genome is largely composed of highly conserved sequences, while the mitochondrial genome is largely composed of poorly conserved sequences - Answers The mitochondrial genome is largely composed of highly conserved sequences, while the nuclear genome is largely composed of poorly conserved sequences Segmental duplications (select all that apply): Can create chimeric genes Have been associated with disorders like autism Have helped shape the human genome Are defined as duplications of > 1 kb with > 90% identity - Answers Can create chimeric genes Have been associated with disorders like autism Have helped shape the human genome Are defined as duplications of > 1 kb with > 90% identity Long non-coding RNAs (select all that apply): Can be involved in transcriptional control Can be involved in post-transcriptional processing Are likely involved in other processes that we are not aware of Can be involved in chromatin remodelling - Answers Can be involved in transcriptional control Can be involved in post-transcriptional processing Are likely involved in other processes that we are not aware of Can be involved in chromatin remodelling A current controversy in the field of epigenetics is whether: Epigenetic markings actually exist Humans are the only species that have epigenetic gene regulation Epigenetic marks are a cause or a consequence of disease Epigenetic markings are caused by methylation alone - Answers Epigenetic marks are a cause or a consequence of disease Non-coding RNAs are not conserved across species. This makes it difficult to: Determine the order of genes across a chromosome Know which non-coding RNAs are functional Determine RNA secondary structure - Answers Know which non-coding RNAs are functional Pioneer factors: Open closed chromatin so that it is more accessible for transcription

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MGY 250 Unit 2 Quiz Questions with Verified Solutions Latest Update 2025/2026

The most recent estimates indicate that the human genome has a total of ~58,000 genes,
approximately subdivided into:



~30,000 protein-coding genes, ~28,000 pseudogenes

~20,000 protein-coding genes, ~10,000 lncRNAs, ~8000 sncRNAs, ~20,000 pseudogenes

~58,000 protein-coding genes

~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000 pseudogenes -
Answers ~20,000 protein-coding genes, ~15,000 lncRNAs, ~8000 sncRNAs, ~15,000
pseudogenes

Sequencing the human genome provided much information on elements that scientists knew
existed but had little information on the structure of, such as (select all that apply):



Origins of replication

Promoter

Protein binding sites

Enhancers - Answers Origins of replication

Promoter

Protein binding sites

Enhancers

The properties of the human nuclear and mitochondrial genomes are very different. In particular:



The mitochondrial genome is largely composed of highly conserved sequences, while the
nuclear genome is largely composed of poorly conserved sequences

The nuclear genome is largely composed of highly conserved sequences, while the
mitochondrial genome is largely composed of poorly conserved sequences - Answers The
mitochondrial genome is largely composed of highly conserved sequences, while the nuclear
genome is largely composed of poorly conserved sequences

Segmental duplications (select all that apply):

, Can create chimeric genes

Have been associated with disorders like autism

Have helped shape the human genome

Are defined as duplications of > 1 kb with > 90% identity - Answers Can create chimeric genes

Have been associated with disorders like autism

Have helped shape the human genome

Are defined as duplications of > 1 kb with > 90% identity

Long non-coding RNAs (select all that apply):



Can be involved in transcriptional control

Can be involved in post-transcriptional processing

Are likely involved in other processes that we are not aware of

Can be involved in chromatin remodelling - Answers Can be involved in transcriptional control

Can be involved in post-transcriptional processing

Are likely involved in other processes that we are not aware of

Can be involved in chromatin remodelling

A current controversy in the field of epigenetics is whether:



Epigenetic markings actually exist

Humans are the only species that have epigenetic gene regulation

Epigenetic marks are a cause or a consequence of disease

Epigenetic markings are caused by methylation alone - Answers Epigenetic marks are a cause
or a consequence of disease

Non-coding RNAs are not conserved across species. This makes it difficult to:

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