NR-507 FINAL EXAM: ADVANCED
PATHOPHYSIOLOGY, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
AT CHAMBERLAIN UNIVERSITY
Gastrointestinal System, Mental Health & Neuro, Neurology (Advanced), Cardiovascular,
Endocrine System, Renal, Respiratory, Immunology, Reproductive, Endocrine System,
Hematology, Oncology, Fluid & Electrolytes, Genetics, Neuro & Psych Advanced,
Musculoskeletal, Pregnancy Pathophysiology
ADVANCED PATHOPHYSIOLOGY
100 Final Exam MCQs
,Answers
Gastrointestinal System
1. The characteristic manifestation of a duodenal ulcer is:
A. Chronic intermittent epigastric pain
B. Pain immediately after eating
C. Hematemesis
D. Nocturnal diarrhea
Answer: A
Rationale: Duodenal ulcer pain is classically intermittent and epigastric.
2. Duodenal ulcer pain typically begins:
A. Immediately after food intake
B. 30 min–2 hrs after eating
C. Only when lying down
D. Only during the day
Answer: B
Rationale: Pain begins when stomach is empty (1–2 hrs post-meal).
3. Peptic ulcers are best described as:
A. Viral erosions in the mucosa
B. Breaks in the mucosal lining of GI tract
C. Hyperplastic mucosal growths
D. Autoimmune inflammation
Answer: B
,4. What type of ulcer is most likely to occur in the large intestine?
A. Peptic ulcer
B. Stress ulcer
C. Ischemic ulcer
D. Ulcerative colitis ulceration
Answer: D
Rationale: Peptic ulcers occur in stomach/duodenum; large intestine ulcers are
due to inflammatory bowel disease.
5. A common cause of gastric ulcers is:
A. High fiber diet
B. H. pylori infection
C. High calcium intake
D. Viral infection
Answer: B
6. Upper GI bleeding is commonly indicated by:
A. Bright red stools
B. Melena
C. Clay-colored stools
D. Hematuria
Answer: B
7. The major risk factor for duodenal ulcers is:
, A. NSAID use
B. Lack of fiber
C. Aging
D. Diabetes
Answer: A >>> The major risk factor for duodenal ulcers is H. pylori infection.
While Nonsteroidal Anti-inflammatory Drug (NSAID) use is also a significant cause, the vast
majority of duodenal ulcers are associated with Helicobacter pylori bacteria. H. pylori infection
accounts for approximately 90% of duodenal ulcers.
Therefore, among the options provided:
A. NSAID use is the second most common cause, but not the major one overall
for duodenal ulcers specifically.
B. Lack of fiber: Diet does not directly cause ulcers, though a high-fiber diet may be
protective.
C. Aging: Duodenal ulcers are most commonly diagnosed in people aged 20 to 45.
D. Diabetes: This is a comorbidity that increases risk of complications, but not the primary
risk factor for the ulcer itself
8. Crohn’s disease uniquely presents with:
A. Continuous colon lesions
B. Skip lesions
C. Only rectal involvement
D. Mucosa-only inflammation
Answer: B
9. Ulcerative colitis is characterized by:
PATHOPHYSIOLOGY, 2025/2026 WITH
CORRECT/ACCURATE ANSWERS
AT CHAMBERLAIN UNIVERSITY
Gastrointestinal System, Mental Health & Neuro, Neurology (Advanced), Cardiovascular,
Endocrine System, Renal, Respiratory, Immunology, Reproductive, Endocrine System,
Hematology, Oncology, Fluid & Electrolytes, Genetics, Neuro & Psych Advanced,
Musculoskeletal, Pregnancy Pathophysiology
ADVANCED PATHOPHYSIOLOGY
100 Final Exam MCQs
,Answers
Gastrointestinal System
1. The characteristic manifestation of a duodenal ulcer is:
A. Chronic intermittent epigastric pain
B. Pain immediately after eating
C. Hematemesis
D. Nocturnal diarrhea
Answer: A
Rationale: Duodenal ulcer pain is classically intermittent and epigastric.
2. Duodenal ulcer pain typically begins:
A. Immediately after food intake
B. 30 min–2 hrs after eating
C. Only when lying down
D. Only during the day
Answer: B
Rationale: Pain begins when stomach is empty (1–2 hrs post-meal).
3. Peptic ulcers are best described as:
A. Viral erosions in the mucosa
B. Breaks in the mucosal lining of GI tract
C. Hyperplastic mucosal growths
D. Autoimmune inflammation
Answer: B
,4. What type of ulcer is most likely to occur in the large intestine?
A. Peptic ulcer
B. Stress ulcer
C. Ischemic ulcer
D. Ulcerative colitis ulceration
Answer: D
Rationale: Peptic ulcers occur in stomach/duodenum; large intestine ulcers are
due to inflammatory bowel disease.
5. A common cause of gastric ulcers is:
A. High fiber diet
B. H. pylori infection
C. High calcium intake
D. Viral infection
Answer: B
6. Upper GI bleeding is commonly indicated by:
A. Bright red stools
B. Melena
C. Clay-colored stools
D. Hematuria
Answer: B
7. The major risk factor for duodenal ulcers is:
, A. NSAID use
B. Lack of fiber
C. Aging
D. Diabetes
Answer: A >>> The major risk factor for duodenal ulcers is H. pylori infection.
While Nonsteroidal Anti-inflammatory Drug (NSAID) use is also a significant cause, the vast
majority of duodenal ulcers are associated with Helicobacter pylori bacteria. H. pylori infection
accounts for approximately 90% of duodenal ulcers.
Therefore, among the options provided:
A. NSAID use is the second most common cause, but not the major one overall
for duodenal ulcers specifically.
B. Lack of fiber: Diet does not directly cause ulcers, though a high-fiber diet may be
protective.
C. Aging: Duodenal ulcers are most commonly diagnosed in people aged 20 to 45.
D. Diabetes: This is a comorbidity that increases risk of complications, but not the primary
risk factor for the ulcer itself
8. Crohn’s disease uniquely presents with:
A. Continuous colon lesions
B. Skip lesions
C. Only rectal involvement
D. Mucosa-only inflammation
Answer: B
9. Ulcerative colitis is characterized by:
