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INBDE Orthodontics NBDE II Review - Prosthodontics Perio Study
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Practice questions for this set
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Exist in cells to guide the proper folding of polypeptide (Hsp70 and Hsp60)
Choose an answer
The sequence of the template DNA strand
1 Molecular Chaperones 2 is 5'-CTGA-3'. What is the sequence of the
mRNA?
3 Pre-mRNA 4 Pol I makes:
Don't know?
Terms in this set (112)
The sequence of the template 5'-UCAG-3'
DNA strand is 5'-CTGA-3'. What
is the sequence of the mRNA?
the DNA strand that has the SAME nucleotide order as the
Coding Strand
mRNA from 5' to 3'
the actual strand that is used as the template for RNA synthesis
Template Strand
(non-coding) and is complementary to the mRNA
1. Binding
2. Initiation
Four steps of Transcription
3. Elongation
4. Termination
Pol I makes: most rRNAs - promoter upstream
Pol II makes: mRNA, snRNA and niRNA - promoter upstream
tRNA and one type of rRNA - promoter is within the transcription
Pol III makes:
unit
TFIID TATA box binding
, Helicase- melts promoter region
TFIIH
Kinase-phosphorylates Pol II
Transcription by pol I is a protein that recognizes an 18-nucleotide signal in the growing
terminated by: RNA chain
Transcription of Pol III is termination signals include short run of Us and no protein facts
terminated by: are required
Transcription of Pol II os cleavage at a specific site before transcription ceases (10-35
terminated by: nucleotides downstream)
crude produce of Pol II transcription, needs further processing
Pre-mRNA
to be mRNA (poly A tail, 5' cap, splicing)
Polyadenylation addition of a poly A tail to the 3' end of mRNA strand
addition of a 5' cap to the 5' end. Note the 5'-5' linkage. Adds
5' capping
stability and ribosome position
Splicing removal of introns and connection of the exons
use of alternative axons generates mRNAs that encode different
Alternative Splicing
iso forms of a protein. Use the same RNA for multiple purposes
Carry out reverse transcriptase (RNA-DNA). Integrate DNA into
Retrovirus host genome (Provirus). Transcription of provirus to make more
viral RNA (DNA-RNA)
T/F Processing of rRNA is the False - rRNA does not combine after spacers are removed
same as processing of mRNA
APOBEC3G edits the HIV genome to dehabilitate a virus
Vif protein An HIV protein that counteracts APOBEC3G
miRNA regulate gene expression mainly by suppressing translation
1. Triplet Code with start and stop codons
The Genetic Code is: 2. Nonoverlapping
3. Degenerate
A stretch of DNA without any stop codon. (usually only part of
Open reading frame
the mRNA)
Sickle cell anemia caused by a single mutation in the B hemoglobin gene (HBB)
unusual base pairing can be formed at the THIRD position of the
Wobble Hypothesis
codon
link amino acids to correct tRNA. ATP driven reaction to link A.A
Aminoacyl-tRNA synthetase
to tRNA and high energy ester bond formed
AUG needed.
1. Methionyl tRNA bound by eIFs
2. Methionyl tRNA bind to the small subunit
Initiation
3. This binds to the 5'cap of the mRNA
4. Find Kozak sequence
5. tRNA base-pairs with start codon, then large subunit
Elongation sequential cycles and is facilitated by elongation factors
done by reaching a stop codon and causes a release factor to
Termination
separation
A nonsense mutation is one that B. Premature termination of translation
causes
A. incorporation of the wrong
amino acid at one position in a
polypeptide
B. premature termination of
translation
C. either A or B
lead to an incomplete, nonfunctional polypeptide (premature
Nonsense Mutations
stop codon formed)