APhA Immunization Exam| Brand
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The National Vaccine Advisory Committee 2013 Standards for Adult Immunization
Practice and the 2016 International Pharmaceutical Federation global report identify
pharmacists as: - Answer✅✅Integral to increasing vaccination rates
Under the direction of the U.S. Department of Health and Human Services, the
Healthy People initiative has identified the following as a goal for 2030: -
Answer✅✅Increase the proportion of persons who are vaccinated annually against
seasonal influenza
Opportunities for Advocacy and Collaboration include: - Answer✅✅Membership in
state Immunization coalition to serve as an expert on policy and practice issues
affecting pharmacy
Which of the following diseases have been eradicated worldwide, allowing
vaccination to be discontinued? - Answer✅✅Smallpox - eradicated in 1980 by WHO
Which of the following is one of the five guidelines identified by the APhA Board of
Trustees in 2019 to assist pharmacists in incorporating immunization activities into
their practice? - Answer✅✅Prevention, Partnership, Quality, Documentation and
Empowerment
,Active Immunity - Answer✅✅Long-term protection but takes 2 weeks to work
Innate Immunity - Answer✅✅Barrier defense mechanism
Adaptive Immunity - Answer✅✅Also known as acquired
Passive Immunity - Answer✅✅Antibodies from an external source
Antigens - Answer✅✅Evoke the immune response and bind to specific antibodies
T/F: Vaccines contain antibodies which are recognized by the immune system. -
Answer✅✅False
What can a pharmacist do to reduce the risk of getting hepatitis B after exposure? -
Answer✅✅1. Post-exposure prophylaxis is needed right away
2. Give both Hep B immune globulin (HBIG) and Hepatitis B vaccine
3. HBIG contains antibodies that provide immediate protection via passive immunity
4. When a person is fully vaccinated, the hepatitis B vaccine provides long-term
protection.
Live Vaccines are: - Answer✅✅1. Attenuated
2. Stimulates both humoral and cell-mediated immune response
3. May be interfered with by circulating antibodies
4. Not given to children less than 12 months of age due to presence of maternal
antibodies
Inactivated Vaccines are: - Answer✅✅1. Killed virus or bacteria
2. Does not replicate
3. Stimulates humoral immunity (antibodies)
4. May be given to people who have received blood products or live vaccines,
regardless of timing.
5. Predominantly given to infants (less than 12 months) because they may have
circulating maternal antibodies which could reduce the effectiveness of a live
vaccines.
T/F: Inactivated vaccines do NOT have minimum intervals between administered
vaccines - Answer✅✅True
T/F: Inactivated vaccines are not affected by live vaccines and visa versa. -
Answer✅✅True
If two live vaccines are given simultaneously sly on the same day, then you must
wait _____ minimum interval. - Answer✅✅28-day minimum interval so that each
vaccine can replicate properly.
Live vaccines followed by blood products (contain antibodies) require
______minimum interval. - Answer✅✅2 weeks.
, Which of the following is an example of passive immunity?
a.) Contracting measles
b.) Hep B Vaccine
c.) Skin Barrier
d.) Maternal antibodies - Answer✅✅d.) Maternal antibodies
Why is spacing and timing of vaccines important? - Answer✅✅Circulating
antibodies may interfere with immune response
How long does it take for the immune system to provide protection by producing
disease-specific antibodies and memory cells? - Answer✅✅14 days
When does Active Immunity occur? - Answer✅✅When a patient is exposed to an
antigen that triggers the body's immune system to produce it's own disease-specific
antibodies and memory cells.
Children less than what age do not mount an adequate immune response to t-cell
independent immunity? - Answer✅✅2 years.
Which of the following is found in vaccines to evoke an immune response? -
Answer✅✅Antigens
What does attenuated mean? - Answer✅✅weakened
LAIV4 is the abbreviation for: - Answer✅✅Live Attenuated Influenza Vaccine
RV1, RV5 is the abbreviation for: - Answer✅✅Rotavirus
VAR is the abbreviation for: - Answer✅✅Varicella
MMR is the abbreviation for: - Answer✅✅Measles, mumps, rubella
MMRV is the abbreviation for: - Answer✅✅Measles, mumps, rubella, varicella
Can inactivated vaccines replicate? - Answer✅✅No. It does not cause disease.
What are two broad categories that vaccines are classified as? - Answer✅✅1. Live
attenuated vaccines
2. Inactivated vaccines
Cellular Vaccines - Answer✅✅1. Inactivated Vaccines
2. Whole viruses or bacteria
3. Known as Subunits (fractions)
4. DTP/DTaP
Toxoid Vaccines - Answer✅✅1. Inactivated Vaccine
, 2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
Recombinant Vaccine - Answer✅✅1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a virus
3. HepB, HPV, RZV, RIV4
What clinical factors need to be considered before administering a lie attenuated
vaccine? - Answer✅✅1. Patients who currently are immunocompromised
2. Live attenuated vaccines administered in the previous 28 days.
T/F: MMR is a live attenuated vaccine. - Answer✅✅True
Which of the following vaccines listed is a live attenuated vaccine?
a.) Hep B
b.) Hep A
c.) RZV
d.) VAR - Answer✅✅d.) VAR
Pneumococcal polysaccharide vaccine (PPSV23) is best categorized as what type of
vaccine? - Answer✅✅Inactivated Polysaccharide Vaccine
Which of the following is true regarding the use of mRNA in vaccine technology?
a.) mRNA is extremely stable in a host's body.
b.) mRNA is the genetic blueprint that tells your body how to make a particular
protein subunit of a virus which, after being produced, will elicit an immune
response.
c.) mRNA vaccine technology requires replication similar to a live attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response and protects the host by
altering the host's DNA. - Answer✅✅b.) mRNA is the genetic blueprint that tells
your body how to make a particular protein subunit of a virus which, after being
produced, will elicit an immune response.
Which vaccine technol is an ingredient added typically to inactivated vaccines to
boost its immune response by targeting pathogen recognition receptors that are
expressed on dendritic cells to trigger a pro-inflammatory response? Though this
technology creates a more robust immune response, it can also increase local site
reactions and systemic reactions, such as fevers, chills, and body aches. -
Answer✅✅Adjuvants (manufactured to produce a more robust immune response
to the vaccine)
When administering measles, mumps, rubella (MMR) and pneumococcal conjugate
vaccine (PCV13) to a patient at their 15-month appointment, what must be
considered regarding vaccine spacing? - Answer✅✅MMR and PCV13 may be
administered simultaneously or at any interval between doses.
New Exam Questions with100%
Correct Clear Answers| All Graded
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Guaranteed Success.
The National Vaccine Advisory Committee 2013 Standards for Adult Immunization
Practice and the 2016 International Pharmaceutical Federation global report identify
pharmacists as: - Answer✅✅Integral to increasing vaccination rates
Under the direction of the U.S. Department of Health and Human Services, the
Healthy People initiative has identified the following as a goal for 2030: -
Answer✅✅Increase the proportion of persons who are vaccinated annually against
seasonal influenza
Opportunities for Advocacy and Collaboration include: - Answer✅✅Membership in
state Immunization coalition to serve as an expert on policy and practice issues
affecting pharmacy
Which of the following diseases have been eradicated worldwide, allowing
vaccination to be discontinued? - Answer✅✅Smallpox - eradicated in 1980 by WHO
Which of the following is one of the five guidelines identified by the APhA Board of
Trustees in 2019 to assist pharmacists in incorporating immunization activities into
their practice? - Answer✅✅Prevention, Partnership, Quality, Documentation and
Empowerment
,Active Immunity - Answer✅✅Long-term protection but takes 2 weeks to work
Innate Immunity - Answer✅✅Barrier defense mechanism
Adaptive Immunity - Answer✅✅Also known as acquired
Passive Immunity - Answer✅✅Antibodies from an external source
Antigens - Answer✅✅Evoke the immune response and bind to specific antibodies
T/F: Vaccines contain antibodies which are recognized by the immune system. -
Answer✅✅False
What can a pharmacist do to reduce the risk of getting hepatitis B after exposure? -
Answer✅✅1. Post-exposure prophylaxis is needed right away
2. Give both Hep B immune globulin (HBIG) and Hepatitis B vaccine
3. HBIG contains antibodies that provide immediate protection via passive immunity
4. When a person is fully vaccinated, the hepatitis B vaccine provides long-term
protection.
Live Vaccines are: - Answer✅✅1. Attenuated
2. Stimulates both humoral and cell-mediated immune response
3. May be interfered with by circulating antibodies
4. Not given to children less than 12 months of age due to presence of maternal
antibodies
Inactivated Vaccines are: - Answer✅✅1. Killed virus or bacteria
2. Does not replicate
3. Stimulates humoral immunity (antibodies)
4. May be given to people who have received blood products or live vaccines,
regardless of timing.
5. Predominantly given to infants (less than 12 months) because they may have
circulating maternal antibodies which could reduce the effectiveness of a live
vaccines.
T/F: Inactivated vaccines do NOT have minimum intervals between administered
vaccines - Answer✅✅True
T/F: Inactivated vaccines are not affected by live vaccines and visa versa. -
Answer✅✅True
If two live vaccines are given simultaneously sly on the same day, then you must
wait _____ minimum interval. - Answer✅✅28-day minimum interval so that each
vaccine can replicate properly.
Live vaccines followed by blood products (contain antibodies) require
______minimum interval. - Answer✅✅2 weeks.
, Which of the following is an example of passive immunity?
a.) Contracting measles
b.) Hep B Vaccine
c.) Skin Barrier
d.) Maternal antibodies - Answer✅✅d.) Maternal antibodies
Why is spacing and timing of vaccines important? - Answer✅✅Circulating
antibodies may interfere with immune response
How long does it take for the immune system to provide protection by producing
disease-specific antibodies and memory cells? - Answer✅✅14 days
When does Active Immunity occur? - Answer✅✅When a patient is exposed to an
antigen that triggers the body's immune system to produce it's own disease-specific
antibodies and memory cells.
Children less than what age do not mount an adequate immune response to t-cell
independent immunity? - Answer✅✅2 years.
Which of the following is found in vaccines to evoke an immune response? -
Answer✅✅Antigens
What does attenuated mean? - Answer✅✅weakened
LAIV4 is the abbreviation for: - Answer✅✅Live Attenuated Influenza Vaccine
RV1, RV5 is the abbreviation for: - Answer✅✅Rotavirus
VAR is the abbreviation for: - Answer✅✅Varicella
MMR is the abbreviation for: - Answer✅✅Measles, mumps, rubella
MMRV is the abbreviation for: - Answer✅✅Measles, mumps, rubella, varicella
Can inactivated vaccines replicate? - Answer✅✅No. It does not cause disease.
What are two broad categories that vaccines are classified as? - Answer✅✅1. Live
attenuated vaccines
2. Inactivated vaccines
Cellular Vaccines - Answer✅✅1. Inactivated Vaccines
2. Whole viruses or bacteria
3. Known as Subunits (fractions)
4. DTP/DTaP
Toxoid Vaccines - Answer✅✅1. Inactivated Vaccine
, 2. Subunit (fractions)
3. Inactive or biological toxin
4. Tetanus toxoid
Recombinant Vaccine - Answer✅✅1. Produced by genetic engineering
2. May contain no actual virus or a modified strain of a virus
3. HepB, HPV, RZV, RIV4
What clinical factors need to be considered before administering a lie attenuated
vaccine? - Answer✅✅1. Patients who currently are immunocompromised
2. Live attenuated vaccines administered in the previous 28 days.
T/F: MMR is a live attenuated vaccine. - Answer✅✅True
Which of the following vaccines listed is a live attenuated vaccine?
a.) Hep B
b.) Hep A
c.) RZV
d.) VAR - Answer✅✅d.) VAR
Pneumococcal polysaccharide vaccine (PPSV23) is best categorized as what type of
vaccine? - Answer✅✅Inactivated Polysaccharide Vaccine
Which of the following is true regarding the use of mRNA in vaccine technology?
a.) mRNA is extremely stable in a host's body.
b.) mRNA is the genetic blueprint that tells your body how to make a particular
protein subunit of a virus which, after being produced, will elicit an immune
response.
c.) mRNA vaccine technology requires replication similar to a live attenuated vaccine.
d.) mRNA vaccine technology elicits its immune response and protects the host by
altering the host's DNA. - Answer✅✅b.) mRNA is the genetic blueprint that tells
your body how to make a particular protein subunit of a virus which, after being
produced, will elicit an immune response.
Which vaccine technol is an ingredient added typically to inactivated vaccines to
boost its immune response by targeting pathogen recognition receptors that are
expressed on dendritic cells to trigger a pro-inflammatory response? Though this
technology creates a more robust immune response, it can also increase local site
reactions and systemic reactions, such as fevers, chills, and body aches. -
Answer✅✅Adjuvants (manufactured to produce a more robust immune response
to the vaccine)
When administering measles, mumps, rubella (MMR) and pneumococcal conjugate
vaccine (PCV13) to a patient at their 15-month appointment, what must be
considered regarding vaccine spacing? - Answer✅✅MMR and PCV13 may be
administered simultaneously or at any interval between doses.
