HESI Pharmacology Exit Exam
What is the indication for metoclopramide/reglan?: Prevention of
chemotherapy-induced emesis and diabetic gastroparesis
What labs need to be evaluated when given aminoglycosides (-mycin,-
micin)?: BUN and creatinine
DOC for MRSA: vancomycin
What is MRSA: severe staph infections that have become resistant to
most antibiotics
Implications for giving vancomycin: acute care requires frequent
monitoring og serum drug level for dose adjustment. Peak and trough
schedule. Trough is drawn just prior to next dose.
Risks when using vancomycin: nephrotoxicity and ototoxicity
SE of vancomycin: thrombophlebitis, red man syndrome if infused too
rapidly: flushing or rash of upper body, dyspnea, itching, hypotension-
can be lethal
How long should IV vancomycin infuse?: greater than 60 minutes
What is trimethoprim/sulfamethoxazole?: it is a sulfonamide for
treatment of UTI. Combination increases efficacy and inhibits
metabolism of folic acid at two different points
What is trimethoprim/sulfamethoxazole known for?: sulfa allergy
, Nursing implications for trimethoprim/sulfamethoxazole: assess for
rash due to potential for stevens johnson syndrome
Penicillins have a ____ to ____: cross-sensitivity; cephalosporins.
They are structurally similar.
Nursing considerations for penicillins: observe respiratory status for
first 30 minutes when administering for the first time. Watch for
anaphylaxis if allergic to one or the other may have cross sensitivity
What can a nurse treat penicillin anaphylaxis with?: epinephrine
Nursing considerations for antibiotics: do not take for viral illnesses.
Take entire prescription as ordered. Don't take if not needed as it can
produce resistance.
What is ribavirin(copegus) indicated for?: antiviral for treatment of
hepatitis C that has failed other treatment
Ribavirin(copegus) SE: hemolytic anemia
What is ticarcillin/clavulanic acid (timentin)?: broad spectrum/extended
spectrum penicillins
Nursing considerations for ticarcillin/clavulanic acid (timentin): do not
administer
In same infusion with aminoglycosides
, What is the indicated use for rifampin?: antitubercular for treatment of
TB
Rifampin SE: turns: body fluids; tears, saliva, urine, soft contacts
red/orange/brown. (ADVISE PT THIS IS NORMAL). Teratogenic- may
decrease effectiveness of oral contraceptives; advise to use
nonhormonal form of conception throughout therapy. Hepatotoxicity
What labs need to be monitored with rifampin?: lfts
What is the indicated use for isoniazid (INH): TB
What does isoniazid (INH) interact with?: foods containing tyramine;
can produce life-threatening hypertensive crisis.
What should be used with isoniazid (INH)?: 2nd form of birth control
Flu vaccine SE: for anyone 6 months and older every season;
soreness, redness and swelling at site of injections, low grade fever,
aches.
What is the indicated use for fluconazole (diflucan)?: antifungal for
vaginal candidiasis
What labs should be monitored with fluconazole (diflucan)?: many
antifungals can cause liver injury monitor lfts
What is antifunal terbinafine (lamisil) used to treat?: superficial
dermatologic infections (athlete's foot) and onychomycosis (nail fungus).
What is the indication for metoclopramide/reglan?: Prevention of
chemotherapy-induced emesis and diabetic gastroparesis
What labs need to be evaluated when given aminoglycosides (-mycin,-
micin)?: BUN and creatinine
DOC for MRSA: vancomycin
What is MRSA: severe staph infections that have become resistant to
most antibiotics
Implications for giving vancomycin: acute care requires frequent
monitoring og serum drug level for dose adjustment. Peak and trough
schedule. Trough is drawn just prior to next dose.
Risks when using vancomycin: nephrotoxicity and ototoxicity
SE of vancomycin: thrombophlebitis, red man syndrome if infused too
rapidly: flushing or rash of upper body, dyspnea, itching, hypotension-
can be lethal
How long should IV vancomycin infuse?: greater than 60 minutes
What is trimethoprim/sulfamethoxazole?: it is a sulfonamide for
treatment of UTI. Combination increases efficacy and inhibits
metabolism of folic acid at two different points
What is trimethoprim/sulfamethoxazole known for?: sulfa allergy
, Nursing implications for trimethoprim/sulfamethoxazole: assess for
rash due to potential for stevens johnson syndrome
Penicillins have a ____ to ____: cross-sensitivity; cephalosporins.
They are structurally similar.
Nursing considerations for penicillins: observe respiratory status for
first 30 minutes when administering for the first time. Watch for
anaphylaxis if allergic to one or the other may have cross sensitivity
What can a nurse treat penicillin anaphylaxis with?: epinephrine
Nursing considerations for antibiotics: do not take for viral illnesses.
Take entire prescription as ordered. Don't take if not needed as it can
produce resistance.
What is ribavirin(copegus) indicated for?: antiviral for treatment of
hepatitis C that has failed other treatment
Ribavirin(copegus) SE: hemolytic anemia
What is ticarcillin/clavulanic acid (timentin)?: broad spectrum/extended
spectrum penicillins
Nursing considerations for ticarcillin/clavulanic acid (timentin): do not
administer
In same infusion with aminoglycosides
, What is the indicated use for rifampin?: antitubercular for treatment of
TB
Rifampin SE: turns: body fluids; tears, saliva, urine, soft contacts
red/orange/brown. (ADVISE PT THIS IS NORMAL). Teratogenic- may
decrease effectiveness of oral contraceptives; advise to use
nonhormonal form of conception throughout therapy. Hepatotoxicity
What labs need to be monitored with rifampin?: lfts
What is the indicated use for isoniazid (INH): TB
What does isoniazid (INH) interact with?: foods containing tyramine;
can produce life-threatening hypertensive crisis.
What should be used with isoniazid (INH)?: 2nd form of birth control
Flu vaccine SE: for anyone 6 months and older every season;
soreness, redness and swelling at site of injections, low grade fever,
aches.
What is the indicated use for fluconazole (diflucan)?: antifungal for
vaginal candidiasis
What labs should be monitored with fluconazole (diflucan)?: many
antifungals can cause liver injury monitor lfts
What is antifunal terbinafine (lamisil) used to treat?: superficial
dermatologic infections (athlete's foot) and onychomycosis (nail fungus).
