COMPREHENSIVE EXAM 2026
◉ Antipsychotic medication provides D2 blockage in the meso-
coritcal pathway causing which of the following effects?
A. reduces negative symptoms
B. Increases EPS
C. causes prolactinemia
D. reduces positive symptoms. Answer: A. reduces negative
symptoms
B. Increases EPS
C. causes prolactinemia
D. reduces positive symptoms
◉ Phencyclidine (PCP) and ketamine exert their unique behavioral
effects by blocking which of the following receptors?
A. GABA
B. serotonin
C. dopamine receptors
D. NMDA type receptors. Answer: A. GABA
,B. serotonin
C. dopamine receptors
D. NMDA type receptors
◉ The diagnosis used to describe a syndrome characterized by
specific s/s resulting from recent ingestion or exposure to a
substance is known as which of the following?
A. substance intoxication
B. substance withdrawal
C. substance use disorder
D. all of the above. Answer: A. substance intoxication (Sadock p. 269)
B. substance withdrawal
C. Substance Use disorder
D. all of the above
◉ Abnormal involuntary movements in a rhythmic pattern affecting
the face, mouth, tongue, and jaw is known as which of the following?
A. akathisia
B. dystonia
C. tardive dyskinesia
,D. EPS. Answer: A. akathisia
B. dystonia
C. tardive dyskinesia
D. EPS
◉ A deeply held belief despite evidence to the contrary, lasting at
least 1 month, without prominent hallucinations, with functional
impairment that relates to the delusional system disorder called?
A. schizophrenia
B. delusional disorder
C. brief psychotic disorder
D. schizophreniform disorder. Answer: A. schizophrenia
B. delusional disorder
C. brief psychotic disorder
D. schizophreniform disorder
◉ Which of the following is true about preoccupation with
castration?
A. this can be serious and life-threatening if castration is carried out
without medical supervision
B. consistent with transvestic disorder
, C. other specified paraphilic disorder
D. sexual masochism disorder. Answer: A. this can be serious and
life-threatening if castration is carried out without medical
supervision
B. consistent with transvestic disorder
C. other specified paraphilic disorder
D. sexual masochism disorder
◉ Which of the following is a system that provides a uniform
language for describing medical and surgical procedures and
diagnostics services rendered by clinicians?
A. HIPPA
B. CPT
C. DSM-5
D. DRG. Answer: A. HIPPA
B. CPT
C. DSM-5
D. DRG
◉ A patient on Chlorpromazine states his orgasm is dry and
afterwards he will commonly have milky urine. The APRN realizes
this is which of the following?