Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
The ability of the anesthetic to penetrate the axon membrane is determined by 3
properties. What are they? - correct answer Molecular size, Lipid solubility, degree of
ionization at tissue pH
Why is epinephrine given with local anesthetics? - correct answer Decreases local
blood flow (decreased risk of bleeding)
Delays systemic absorption of the anesthetic
prolongs anesthesia
reduces the risk of toxicity
What is the most widely used local anesthetic? - correct answer Lidocaine
What is a possible fatal reaction to benzocaine - correct answer Methemoglobinemia
What is included in application guidelines for topical anesthetics - correct answer
avoid wrapping the site and heating the site, avoid application to open skin
Which medication will not cause rebound headaches from overuse? - correct answer
propranolol (preventative)
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
What is the best option for menstural migraine? - correct answer low dose estrogen
about 3 days prior to menses
What food can trigger migraines? - correct answer Hot dog d/t nitrates
What medication is a Seratonin 1B1D receptor agonist? - correct answer Sumatriptan
Butterbur can help as prevention for migraine therapy. What side effect can occur? -
correct answer Liver damage
What are the 3 main classes of opiod receptors? - correct answer Mu kappa delta
Which of the following will reserve he effects caused by opioid agonist? - correct
answer naloxone
Which of the medications are used to treat OIC? - correct answer Naloxegol,
methylinaltrexone, lubiprostone
Prescribing basics - correct answer Prescribing is regulated by state BON
Proper RX - correct answer Providers name and address, Telephone
DEA
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
Pt name/DOB/Addres
Name of Drug, strength, SIG(directions) with indication/Route and frequency,
Quantity and signature.
Drug Schedules: Most addictive to least - correct answer 1: Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine, methadone, oxycodone, meperidine,
fentanyl, adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol
5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - correct answer The effects of drug on the body. Receptors are
large molecules usually proteins, that interact and mediate the action of drugs
agonist - correct answer produce receptor stimulation and a conformational change
every time they bind. Do not need all available receptors to produce a maximum
response
Partial agonist - correct answer drugs that have properties in b/w those of full
agonist and antagonist. They bind to receptors but when they occupy the receptor
sites, they stimulate only some of the receptors.
, NURS 5334 Advanced Pharm: Final Exam
Questions and Answers {latest update
2026-2027} 100% Correct – UTA.
antagonist - correct answer drugs with affinity for a receptor but with no intrinsic
activity. Affinity allows the antagonist to bind to receptors, but lack of intrinsic
activity prevents the bound antagonist from causing receptor activation. The block
action of drugs (ex. Narcan)
Bioavailabity - correct answer % of administered dosage of the drug that survives the
first pass through the liver and reaches the blood stream
half life - correct answer Time required for the amount of a drug in the body to
decline by 50%, drugs with shorter half lives must be administer frequently. 4.5-5.5
times the half life to get steady state and to be limited from the body
what the body does to the drug - correct answer absorption, distribution,
metabolism, excretion
Distribution - correct answer movement of absorbed drug in bodily fluids
throughout the body to target tissue. Properties affecting: lipid/water solubility, PH
affects ionization of drug, protein binding, size of molecule (smaller molecules are
more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble will pass), placental barrier
(many drugs can pass)