Blood Bank UAMS Exam 2 Questions and
Answers (100% Correct Answers) Already
Graded A+
Enzyme Treatment Enhances Which antibodies? [ Ans: ]
Rh, Kidd
Enzyme treatment destroys which antibodies [ Ans: ] MNS
and Duffy
What % of the population is positive for Rh "D" antigen? [
Ans: ] 85%
What % of the population is positive for the "e" Rh
antigen? [ Ans: ] 98%
What % of the population is negative for the "C" Rh
antigen? [ Ans: ] 30%
What does the "d" represent with regards to the Rh group
of antigen? [ Ans: ] It is amorphic. It's basically a
placeholder. "d" does not exist
Wiener R1 is what in Fisher-Race? [ Ans: ] DCe
Wiener r' is what in Fisher Race [ Ans: ] dCe
Wiener R0 is what in Fisher Race [ Ans: ] Dce
Wiener ry is what in Fisher Race [ Ans: ] dCE
,Wiener R2 is what in Fisher Race [ Ans: ] DcE
Wiener Rz is what in Fisher Race [ Ans: ] DCE
Wiener r" is what in Fisher Race [ Ans: ] dcE
Wiener r is what in Fisher Race [ Ans: ] dce
If a patient is genotyped as AO what is their phenotype? [
Ans: ] A
If a patient is genotyped as hh, AO what is their
phenotype? [ Ans: ] They will appear as type O due to no
H antigens
What is D mosaic (partial D) [ Ans: ] Patient is lacking part
of the "D" molecule. They will type as D+ but can make
antibodies to the part they are lacking
What does Rh null mean [ Ans: ] Patient is lacking Rh
antigens
What are the two process that result in an Rh null patient?
[ Ans: ] RHAG located on chromosome 6 is lacking
(regulator gene)
There are two amorphic recessive genes
What % of the population is positive for the "E" Rh antigen
[ Ans: ] 30%
, What % of the population is negative for the "c" Rh
antigen? [ Ans: ] 20%
What is a cause for a weak D expression [ Ans: ] Inherited
a weakened expression of D antigen
True/False: A weakened expression of D antigen can be
caused by the C antigen inherited in the cis position on
the gene [ Ans: ] False: Trans position
Rh null red blood cells can lead to dehydration, decreased
surface:volume ratio and increased stomatocytes with
increased osmotic fragility. Why? [ Ans: ] The cells are
missing the Rh antigens and LW and Fy5 antigens which
are usually incorporated in the structural proteins of the
cells
Why would there be a false positive Rh with slide or rapid
tube testing? [ Ans: ] High protein medium, increased
proteins can cause false agglutinatiln
What is a chemically modified IgG antisera? [ Ans: ] The
IgG antibody is modified at the disulfide bond to open it
up so it acts like an IgM antibody
What is polyclonal IgG antisera used for when initial blood
typing [ Ans: ] Weak D testing
When doing weak D testing, what should be considered if
the control is positive at any stage? [ Ans: ] A positive DAT
is possible
Answers (100% Correct Answers) Already
Graded A+
Enzyme Treatment Enhances Which antibodies? [ Ans: ]
Rh, Kidd
Enzyme treatment destroys which antibodies [ Ans: ] MNS
and Duffy
What % of the population is positive for Rh "D" antigen? [
Ans: ] 85%
What % of the population is positive for the "e" Rh
antigen? [ Ans: ] 98%
What % of the population is negative for the "C" Rh
antigen? [ Ans: ] 30%
What does the "d" represent with regards to the Rh group
of antigen? [ Ans: ] It is amorphic. It's basically a
placeholder. "d" does not exist
Wiener R1 is what in Fisher-Race? [ Ans: ] DCe
Wiener r' is what in Fisher Race [ Ans: ] dCe
Wiener R0 is what in Fisher Race [ Ans: ] Dce
Wiener ry is what in Fisher Race [ Ans: ] dCE
,Wiener R2 is what in Fisher Race [ Ans: ] DcE
Wiener Rz is what in Fisher Race [ Ans: ] DCE
Wiener r" is what in Fisher Race [ Ans: ] dcE
Wiener r is what in Fisher Race [ Ans: ] dce
If a patient is genotyped as AO what is their phenotype? [
Ans: ] A
If a patient is genotyped as hh, AO what is their
phenotype? [ Ans: ] They will appear as type O due to no
H antigens
What is D mosaic (partial D) [ Ans: ] Patient is lacking part
of the "D" molecule. They will type as D+ but can make
antibodies to the part they are lacking
What does Rh null mean [ Ans: ] Patient is lacking Rh
antigens
What are the two process that result in an Rh null patient?
[ Ans: ] RHAG located on chromosome 6 is lacking
(regulator gene)
There are two amorphic recessive genes
What % of the population is positive for the "E" Rh antigen
[ Ans: ] 30%
, What % of the population is negative for the "c" Rh
antigen? [ Ans: ] 20%
What is a cause for a weak D expression [ Ans: ] Inherited
a weakened expression of D antigen
True/False: A weakened expression of D antigen can be
caused by the C antigen inherited in the cis position on
the gene [ Ans: ] False: Trans position
Rh null red blood cells can lead to dehydration, decreased
surface:volume ratio and increased stomatocytes with
increased osmotic fragility. Why? [ Ans: ] The cells are
missing the Rh antigens and LW and Fy5 antigens which
are usually incorporated in the structural proteins of the
cells
Why would there be a false positive Rh with slide or rapid
tube testing? [ Ans: ] High protein medium, increased
proteins can cause false agglutinatiln
What is a chemically modified IgG antisera? [ Ans: ] The
IgG antibody is modified at the disulfide bond to open it
up so it acts like an IgM antibody
What is polyclonal IgG antisera used for when initial blood
typing [ Ans: ] Weak D testing
When doing weak D testing, what should be considered if
the control is positive at any stage? [ Ans: ] A positive DAT
is possible
