ACTUAL EXAM SCRIPT 2026 QUESTIONS
WITH ANSWERS GRADED A+
◉ 2. Prolonged receptor stimulation during chronic drug therapy
may induce cells to endocytose and sequester drug receptors in
endocytic vesicles. This molecular mechanism is called
A) tachyphylaxis.
B) inactivation.
C) desensitization.
D) downregulation.
E) refractoriness. Answer: D
◉ A 16-year-old female with a history of goiter is admitted with
fever, profuse sweating, tachyarrhythmia, hypertension, abdominal
pain, and anxiety. Based on a working diagnosis of thyrotoxicosis,
she is started on a beta-adrenoceptor antagonist that has a very
short half-life.
24. Refer to the case above. Regarding the mechanism by which the
drug ameliorates the toxic effects of excessive thyroxine levels, the
drug acts as
,A) a physiologic antagonist.
B) a competitive receptor antagonist.
C) a noncompetitive receptor antagonist.
D) a partial agonist.
E) an inverse agonist.. Answer: A
◉ 25. The main pharmacologic effect of norepinephrine on alpha-1
receptors is
A. increased heart rate
B. bronchodilation
C. vasoconstriction
D. contraction of urinary bladder
E. increased force of myocardial contraction. Answer: C
◉ 26. The pharmacologic effect of IV metaraminol (an alpha-1 drug)
is
A. vasodilation
B. vasoconstriction
C. cardiac stimulation
D. cardiac depression
E. bronchodilation. Answer: B
, ◉ 27. Epinephrine stimulates
A. alpha-1 receptors
B. alpha-2 receptors
C. beta-1 receptors
D. beta-2 receptors
E. all of these. Answer: E
◉ 28. At therapeutic doses, albuterol stimulates
A. alpha-1 receptors
B. alpha-2 receptors
C. beta-1 receptors
D. beta-2 receptors
E. all of these. Answer: D
◉ 29. Metoprolol is classified as a(n)
A. alpha-blocker
B. nonselective beta-blocker
C. selective beta-1 blocker
D. adrenergic neuronal blocker
E. selective beta-2 blocker. Answer: C
◉ 30. The mechanism of action of methyldopa is