CHEM 2001 – Exam 2 2025 (50 Questions) | Chromatography, Detectors, Mass Spectrometry

This document provides a complete and verified set of 50 questions and answers for CHEM 2001 – Analytical Chemistry Exam 2 from the 2025/2026 academic year at Georgia State University. The content focuses extensively on chemical separation techniques and instrumental analysis, offering a clear and concise overview of key topics essential to second-year undergraduate chemistry students. The questions cover both conceptual theory and applied knowledge across chromatographic methods (GC, HPLC, TLC, ion exchange, size exclusion, affinity, partition, and adsorption chromatography), as well as detection systems used in modern analysis. These include UV, fluorescence, refractive index, electrochemical, FID, ECD, TCD, mass spectrometry (MS), and specialized ionization methods such as ESI, CI, APPI, and MALDI. Each entry is clearly structured with correct answers indicated for efficient self-assessment. This document is highly suitable for: Undergraduate students taking Analytical Chemistry or Instrumental Analysis courses Chemistry, Biochemistry, Pharmaceutical Science, and Chemical Engineering majors Students preparing for CHEM 2001 midterm or comprehensive assessments at institutions following ACS-based curricula Learners aiming to master qualitative and quantitative analysis tools in laboratory and research settings This exam set is ideal for structured study sessions, last-minute review, or as a checklist to ensure mastery of instrument-based analytical techniques and separation science fundamentals. Keywords: CHEM 2001, analytical chemistry, chromatography, gas chromatography, HPLC, detectors, UV detector, electrochemical detector, mass spectrometry, ion exchange, affinity chromatography, separation techniques, thermal conductivity detector, flame ionization detector, ESI, MALDI,