|Fall 2025/2026 Update | 100% Correct Latest
Question 1
A 28-year-old postpartum woman reports persistent sadness, fatigue, and difficulty bonding
with her infant. She meets criteria for major depressive disorder. What is the first-line
pharmacologic treatment?
A. Bupropion
B. Sertraline
C. Phenelzine
D. Lorazepam
Correct Answer: B
Rationale: Sertraline (an SSRI) is FDA Category C and first-line for postpartum depression due to
low risk to breastfeeding infants and rapid onset. Bupropion is second-line; MAOIs (phenelzine)
and benzos (lorazepam) are avoided in lactation.
Question 2
What is a key barrier to accessing pediatric mental health care in rural communities?
A. Overabundance of specialists
B. Provider shortages and stigma
C. Low insurance copays
D. Excessive telehealth options
Correct Answer: B
,Rationale: Rural areas face provider shortages (e.g., <1 psychiatrist per 10,000 children) and
cultural stigma, per AACN and NR 606 Week 1 content. Telehealth helps but isn't universally
available.
Question 3
A client with postpartum depression screens positive on the Edinburgh Postnatal Depression
Scale (score >13). What is the next step?
A. Immediate hospitalization
B. Comprehensive assessment and referral to psychiatry
C. Prescribe antipsychotics
D. Reassure and follow up in 6 months
Correct Answer: B
Rationale: EPDS >13 indicates high risk; requires full diagnostic evaluation, safety assessment,
and multidisciplinary referral, not acute admission unless suicidal.
Question 4
Which non-pharmacologic intervention is most effective for mild perinatal anxiety?
A. High-intensity interval training
B. Cognitive behavioral therapy (CBT)
C. Electroconvulsive therapy (ECT)
D. Opioid analgesics
Correct Answer: B
Rationale: CBT is evidence-based first-line for perinatal anxiety, reducing symptoms by 50% in
trials (NR 606 Week 2). ECT is for severe cases; others are inappropriate.
,Question 5
A 6-month-old infant cries >3 hours/day for >3 days/week. This presentation is consistent with:
A. Autism spectrum disorder
B. Colic
C. Iron deficiency anemia
D. Gastroesophageal reflux disease (GERD)
Correct Answer: B
Rationale: Colic is defined by the "rule of threes" (NR 606 Week 1 quiz); resolves by 3–4 months.
Rule out organic causes like GERD.
Question 6
In a client with peripartum depression, what lab test should be monitored if starting an SSRI?
A. Complete blood count (CBC)
B. Liver function tests (LFTs)
C. Thyroid-stimulating hormone (TSH)
D. Serum electrolytes
Correct Answer: C
Rationale: Postpartum thyroiditis mimics depression; baseline TSH is essential before SSRIs (NR
606 guidelines).
Question 7
What cultural factor may influence help-seeking in Hispanic perinatal clients?
A. Emphasis on family collectivism
B. Fatalismo (acceptance of fate) and stigma
, C. High trust in biomedical models
D. Preference for individual therapy
Correct Answer: B
Rationale: Fatalismo and machismo contribute to underreporting in Latino communities (Week
2 cultural insights).
Question 8
A breastfeeding mother is prescribed sertraline. What is the primary teaching point?
A. Discontinue breastfeeding immediately
B. Monitor infant for sedation and irritability
C. Switch to formula feeding only
D. Avoid all antidepressants
Correct Answer: B
Rationale: Sertraline has minimal breast milk transfer; monitor infant per AAP guidelines (NR
606 Week 2).
Question 9
Which screening tool is validated for postpartum depression in primary care?
A. GAD-7
B. Patient Health Questionnaire-9 (PHQ-9)
C. Columbia-Suicide Severity Rating Scale (C-SSRS)
D. Mini-Mental State Examination (MMSE)
Correct Answer: B