NR 565-advanced pharmacology midterm Chamberlain NEWEST WITH COMPLETE QUESTIONS AND CORRECT VERIFIED ANSWERS LATEST UPDATE JUST RELEASED THIS YEAR

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NR 565-advanced pharmacology midterm
Chamberlain NEWEST WITH COMPLETE
QUESTIONS AND CORRECT VERIFIED ANSWERS
LATEST UPDATE JUST RELEASED THIS YEAR


Question: Physiological changes during pregnancy that impact pharmacodynamics and

pharmacokinetic properties of drugs? - ANSWER✔✔increase glomerular filtration rate leads to

increase durg excretion


increase hepatic metabolism


decrease tone and motility of bowel


increase drug absorption




Question: Examples of medications that can be teratogenic - ANSWER✔✔Antiepileptic drugs,

antimicrobials such as tetracyclines and fluoroquinolones, vitamin A in large doses, some

anticoagulants, and hormonal medications such as diethylstilbestrol (DES).




Question: How is absorption of intramuscular medications different in neonates? -

ANSWER✔✔slow and erratic due to low blood flow in muscles first few days of life


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Question: Why is absorption of medication in the stomach increased in infancy? -

ANSWER✔✔delayed gastric emptying




Question: Some medications that should be avoided in the pediatric patient? -

ANSWER✔✔glucocorticoids, discoloration of developing teeth with tetracyclines, and

kernicterus with sulfonamides, levofloxacin (antibiotics)


aspirin (Severe intoxication from acute overdose)




Q;During what trimester is a pregnant woman most at risk for adverse drug reactions with

potential long term consequences? - ANSWER✔✔1st trimester (fetus most at risk d/t rapid

growth)




Question: What is BEERS criteria? - ANSWER✔✔Recommendations of medications

inappropriate for elderly (65 and older), prescriber ultimately decides




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Question: What is the CYP450 (cytochrome P450) - ANSWER✔✔liver enzyme system where

medications are metabolized, can either be inducers or inhibitors and create drug-drug

interactions




Question: CYP450 inducers - ANSWER✔✔Speed up metabolism of drugs (drug is cleared

faster), drug has lesser effect (decrease blood levels of drug), elevate CYP450 enzymes




Question: CYP450 inducers pneumonic - ANSWER✔✔"Bullshit Crap GPS INDUCES rage"




Question: CYP450 inducer drug names - ANSWER✔✔Barbituates, St John wort,

Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital, sulfonylureas




Question: CYP450 inhibitors - ANSWER✔✔inhibit metabolism, increase blood levels of

medications




Question: CYP450 pneumonic - ANSWER✔✔"VISA credit card debt INHIBITS spending on

designers like CK to look GQ"



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Question: CYP450 inhibitors drug names - ANSWER✔✔Valproate, isoniazid, sulfonamides,

amiodarone, chloramphenicol, ketoconazole, grapefruit juice, quinidine




Question: what should be included in medication administration patient education? -

ANSWER✔✔dosage size and timing


route and technique of administration


duration of treatment


drug storage


nature and time course of desired responses


nature and time course of adverse responses


finish taking antibiotic




Question: What are some things that put the elderly patient at higher risk for adverse drug

reactions? - ANSWER✔✔reduced renal function


polypharmacy (the use of five or more medications daily)


greater severity of illness

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