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POB SHADWICK EXAM 3 TERMS CORRECT 100%

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DNA polymerase - ANSWERkey enzyme in DNA replication, is what causes complementary base pairing to occur, only goes in one direction DNA helicase - ANSWERunwinds and unzips the DNA helix DNA ligase - ANSWERseals any breaks that were created in the lagging strand between the Okazaki fragments

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POB SHADWICK EXAM 3 TERMS
CORRECT 100%
DNA polymerase - ANSWERkey enzyme in DNA replication, is what causes
complementary base pairing to occur, only goes in one direction

DNA helicase - ANSWERunwinds and unzips the DNA helix

DNA ligase - ANSWERseals any breaks that were created in the lagging strand
between the Okazaki fragments

mRNA - ANSWERcarries genetic information from DNA to ribosomes, created by the
use of RNA polymerase, which stops at its terminator

when transcription stops... - ANSWERa guanine cap is added to the 5' end of the mRNA
and a poly-A tail is added to the 3' end to precent more reactions from occurring

all proteins start with... - ANSWERmethionine, AUG

tRNA - ANSWERtransports the amino acids to the ribosomes, the amino acid binds to
one end and the other end has an anticodon, the order of the mRNA codons decides
the order in which tRNA brings in the amino acids

initiation - ANSWERassemblies the ribosomal components, there are three tRNA
binding sites:
A (amino acid)
P (peptide)
E (exit)

albinism - ANSWERcaused by a faulty enzyme, which is nonfunctional

PKU - ANSWERlack the ability to process phenylalanine due to the lack of an enzyme,
need a special diet in order to develop properly during infancy

purines - ANSWERnucleotide with a double ring structure, adenine and guanine

pyrimidines - ANSWERnucleotides with a single ring in their structure, thymine,
cytosine, and uracil

promoter - ANSWERoperon, where RNA polymerase binds prior to transcription

pre mRNA - ANSWERmRNA produced by transcription that has not yet had its introns
removed

, wobble effect - ANSWERthird nucleotide in a codon can vary and it does not effect the
expression due to there being many codes for the same amino acid

release factor - ANSWERprotein that cleaved polypeptide from the last tRNA

operon - ANSWERgroup of structural and regulating genes that function as a single unit

repressor - ANSWERprevents polymerase from transcribing when it is present

pre transcriptional control - ANSWERie Barr body, using DNA methylation and
chromatin to turn off genes

euchromatin - ANSWERloosely packed chromatin, needs to be unpacked to be
transcribed

epigenetic inheritance - ANSWERwhere a nuclear gene has been modified but the
changed expression is not permanent over generations

transposon - ANSWERDNA sequence capable of randomly moving from one site to
another in the genome

angiogenesis - ANSWERformation of new blood vessels, this happening rapidly is
characteristic of cancer cells

each ribosomal subunit is composed of... - ANSWERrRNA and many proteins

heterochromatin - ANSWERportion of inactive chromatin

interphase - ANSWERthe resting phase between successive mitotic divisions of a cell,
or between the first and second divisions of meiosis. includes G1, S, and G2

G1 - ANSWERdoubles organelles


p53 - ANSWERmajor tumor suppressor gene, mutated in over 50% of cancers

spindle - ANSWERcollection of microtubules that assist in the orderly distribution of
chromosomes during cell division steps of mitosis

crossing over - ANSWERduring prophase 1, exchange of segments between non sister
chromatids of a bivalent during meiosis

interkinesis - ANSWERtime between meiosis 1 and 2, during which no DNA replication
takes place

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