NR605
NR 605 Exam 1 Study Questions and Answers 2026
incidence rate
the number of new cases of a disease (in a specific period: usually a year)
divided by
the number of individuals in a population
prevalence rate
proportion of the population affected by a disease in a given time
-remember if we are good at treating a chronic disease, the prevalence may
be higher
cell injury causes
Depletion of ATP
decreased oxygen in the cell
increased release of free radicals
increased free radicals leads to
increased intracellular calcium
increased cell calcium leads to
defects in cellular membrane
defects in cell membrane lead to
cell death
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,NR605
ABO antigens
Individual receives either A antigen, B antigen or neither (O)
A antigen has
B antibodies
B antigen has
A antibodies
AB antigen has
no antibodies
O antigen
A and B antibodies
Universal donor
O
Universal recipient
AB
immunoglobulins
IgG
IgM,
IgA
IgE
IgD
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, NR605
IgG
most abundant antibody
active agains viruses, bacteria and toxins
IgM
Largest, 1st antibody produced in response to an antigen
Timing of IgG and IgM
refer to photo
IgA
found in secretions and mucous membranes
IgE
active in allergies and parasitic reactions
Causes release of histamine
IgD
activation of B and T cells
Type I Hypersensitivity
IgE mediated
Allergic reactions
with exposure to antigen IgE bind with mast cells causing the release of
histamine
3|Page
NR 605 Exam 1 Study Questions and Answers 2026
incidence rate
the number of new cases of a disease (in a specific period: usually a year)
divided by
the number of individuals in a population
prevalence rate
proportion of the population affected by a disease in a given time
-remember if we are good at treating a chronic disease, the prevalence may
be higher
cell injury causes
Depletion of ATP
decreased oxygen in the cell
increased release of free radicals
increased free radicals leads to
increased intracellular calcium
increased cell calcium leads to
defects in cellular membrane
defects in cell membrane lead to
cell death
1|Page
,NR605
ABO antigens
Individual receives either A antigen, B antigen or neither (O)
A antigen has
B antibodies
B antigen has
A antibodies
AB antigen has
no antibodies
O antigen
A and B antibodies
Universal donor
O
Universal recipient
AB
immunoglobulins
IgG
IgM,
IgA
IgE
IgD
2|Page
, NR605
IgG
most abundant antibody
active agains viruses, bacteria and toxins
IgM
Largest, 1st antibody produced in response to an antigen
Timing of IgG and IgM
refer to photo
IgA
found in secretions and mucous membranes
IgE
active in allergies and parasitic reactions
Causes release of histamine
IgD
activation of B and T cells
Type I Hypersensitivity
IgE mediated
Allergic reactions
with exposure to antigen IgE bind with mast cells causing the release of
histamine
3|Page
