DAVIS ADVANTAGE FOR PATHOPHYSIOLOGY
3RD EDITION 2026 COMPLETE REVIEW |
COMPREHENSIVE CHAPTER STUDY GUIDE ||
UPDATED VERSION
Chapter 1: Introduction to Pathophysiology
1. What is the primary focus of pathophysiology?
A. The study of drug interactions
B. The study of the structural changes caused by disease
C. The study of the functional changes in the body resulting from disease
D. The microscopic examination of tissues
2. The maintenance of a stable internal environment is termed:
A. Hemostasis
B. Homeostasis
C. Metabolism
D. Pathogenesis
3. Which term describes the cause of a disease?
A. Pathogenesis
B. Etiology
C. Prognosis
D. Diagnosis
4. A patient's sudden onset of severe chest pain is an example of:
A. A symptom
B. A sign
C. A syndrome
D. Both a symptom (patient feels) and a sign (can be observed)
5. Cellular adaptation where one cell type is replaced by another is:
A. Atrophy
B. Hypertrophy
C. Metaplasia
D. Dysplasia
,Chapter 2: Fluid, Electrolyte, and Acid-Base Imbalances
6. The primary extracellular cation is:
A. Potassium
B. Chloride
C. Sodium
D. Phosphate
7. Edema caused by low plasma albumin is primarily due to a decrease in:
A. Hydrostatic pressure
B. Capillary permeability
C. Lymphatic flow
D. Plasma oncotic pressure
8. The hallmark laboratory finding in Syndrome of Inappropriate Antidiuretic Hormone
(SIADH) is:
A. Hypernatremia
B. Hyponatremia
C. Hyperkalemia
D. Hypovolemia
9. A patient with diabetic ketoacidosis would most likely present with:
A. Metabolic alkalosis
B. Respiratory alkalosis
C. Metabolic acidosis
D. Respiratory acidosis
10. Compensation for respiratory alkalosis involves:
A. Renal retention of H+ and excretion of HCO3-
B. Renal excretion of H+ and retention of HCO3-
C. Hyperventilation
D. Hypoventilation
Chapter 3: Inflammation and Tissue Repair
11. The first responders to tissue injury are:
A. Lymphocytes
B. Neutrophils
C. Macrophages
D. Eosinophils
,12. The cardinal signs of inflammation are directly caused by:
A. Vasoconstriction and decreased permeability
B. Vasodilation, increased permeability, and leukocyte infiltration
C. Platelet aggregation
D. Collagen deposition
13. Which chemical mediator is primarily responsible for pain in inflammation?
A. Histamine
B. Prostaglandins
C. Bradykinin
D. Cytokines
14. Granulation tissue is characterized by the presence of:
A. Mature collagen and fibroblasts
B. New capillaries and fibroblasts
C. Dense clusters of neutrophils
D. Epithelial cells
15. A keloid scar is an example of:
A. Regeneration
B. Dysfunctional wound healing with excessive collagen deposition
C. Primary intention healing
D. Normal scar formation
Chapter 4: Genetic and Genomic Influences
16. An autosomal dominant disorder means:
A. Two copies of the mutated gene are needed.
B. The gene is on the X chromosome.
C. One copy of the mutated gene from one parent is sufficient to cause the disorder.
D. It only appears in females.
17. Which of the following is an example of a multifactorial inheritance disorder?
A. Cystic Fibrosis (autosomal recessive)
B. Huntington's Disease (autosomal dominant)
C. Down Syndrome (chromosomal)
D. Cleft Lip/Palate
18. A point mutation that results in a stop codon is called a:
A. Missense mutation
B. Silent mutation
, C. Nonsense mutation
D. Frameshift mutation
19. The purpose of a pedigree analysis is to:
A. Sequence an individual's DNA
B. Track the inheritance of a trait within a family
C. Diagnose a specific cancer
D. Treat a genetic disorder
20. Trisomy 21 is the genetic basis for:
A. Turner Syndrome
B. Klinefelter Syndrome
C. Down Syndrome
D. Fragile X Syndrome
Chapter 5: Altered Cellular Function (Cancer)
21. Oncogenes are best described as:
A. Normal genes that inhibit cell division.
B. Mutated or overexpressed genes that promote uncontrolled cell growth.
C. Genes that repair DNA damage.
D. Genes responsible for apoptosis.
22. The process by which cancer cells spread to distant sites is called:
A. Hyperplasia
B. Dysplasia
C. Invasion
D. Metastasis
23. The "T" in the TNM staging system refers to:
A. Tumor size and local invasion
B. Involvement of lymph Nodes
C. Presence of distant Metastasis
D. Tumor grade
24. Paraneoplastic syndromes are:
A. Direct effects of a tumor mass.
B. Side effects of chemotherapy.
C. Remote effects of cancer not related to metastasis.
D. Infections due to immunosuppression.
3RD EDITION 2026 COMPLETE REVIEW |
COMPREHENSIVE CHAPTER STUDY GUIDE ||
UPDATED VERSION
Chapter 1: Introduction to Pathophysiology
1. What is the primary focus of pathophysiology?
A. The study of drug interactions
B. The study of the structural changes caused by disease
C. The study of the functional changes in the body resulting from disease
D. The microscopic examination of tissues
2. The maintenance of a stable internal environment is termed:
A. Hemostasis
B. Homeostasis
C. Metabolism
D. Pathogenesis
3. Which term describes the cause of a disease?
A. Pathogenesis
B. Etiology
C. Prognosis
D. Diagnosis
4. A patient's sudden onset of severe chest pain is an example of:
A. A symptom
B. A sign
C. A syndrome
D. Both a symptom (patient feels) and a sign (can be observed)
5. Cellular adaptation where one cell type is replaced by another is:
A. Atrophy
B. Hypertrophy
C. Metaplasia
D. Dysplasia
,Chapter 2: Fluid, Electrolyte, and Acid-Base Imbalances
6. The primary extracellular cation is:
A. Potassium
B. Chloride
C. Sodium
D. Phosphate
7. Edema caused by low plasma albumin is primarily due to a decrease in:
A. Hydrostatic pressure
B. Capillary permeability
C. Lymphatic flow
D. Plasma oncotic pressure
8. The hallmark laboratory finding in Syndrome of Inappropriate Antidiuretic Hormone
(SIADH) is:
A. Hypernatremia
B. Hyponatremia
C. Hyperkalemia
D. Hypovolemia
9. A patient with diabetic ketoacidosis would most likely present with:
A. Metabolic alkalosis
B. Respiratory alkalosis
C. Metabolic acidosis
D. Respiratory acidosis
10. Compensation for respiratory alkalosis involves:
A. Renal retention of H+ and excretion of HCO3-
B. Renal excretion of H+ and retention of HCO3-
C. Hyperventilation
D. Hypoventilation
Chapter 3: Inflammation and Tissue Repair
11. The first responders to tissue injury are:
A. Lymphocytes
B. Neutrophils
C. Macrophages
D. Eosinophils
,12. The cardinal signs of inflammation are directly caused by:
A. Vasoconstriction and decreased permeability
B. Vasodilation, increased permeability, and leukocyte infiltration
C. Platelet aggregation
D. Collagen deposition
13. Which chemical mediator is primarily responsible for pain in inflammation?
A. Histamine
B. Prostaglandins
C. Bradykinin
D. Cytokines
14. Granulation tissue is characterized by the presence of:
A. Mature collagen and fibroblasts
B. New capillaries and fibroblasts
C. Dense clusters of neutrophils
D. Epithelial cells
15. A keloid scar is an example of:
A. Regeneration
B. Dysfunctional wound healing with excessive collagen deposition
C. Primary intention healing
D. Normal scar formation
Chapter 4: Genetic and Genomic Influences
16. An autosomal dominant disorder means:
A. Two copies of the mutated gene are needed.
B. The gene is on the X chromosome.
C. One copy of the mutated gene from one parent is sufficient to cause the disorder.
D. It only appears in females.
17. Which of the following is an example of a multifactorial inheritance disorder?
A. Cystic Fibrosis (autosomal recessive)
B. Huntington's Disease (autosomal dominant)
C. Down Syndrome (chromosomal)
D. Cleft Lip/Palate
18. A point mutation that results in a stop codon is called a:
A. Missense mutation
B. Silent mutation
, C. Nonsense mutation
D. Frameshift mutation
19. The purpose of a pedigree analysis is to:
A. Sequence an individual's DNA
B. Track the inheritance of a trait within a family
C. Diagnose a specific cancer
D. Treat a genetic disorder
20. Trisomy 21 is the genetic basis for:
A. Turner Syndrome
B. Klinefelter Syndrome
C. Down Syndrome
D. Fragile X Syndrome
Chapter 5: Altered Cellular Function (Cancer)
21. Oncogenes are best described as:
A. Normal genes that inhibit cell division.
B. Mutated or overexpressed genes that promote uncontrolled cell growth.
C. Genes that repair DNA damage.
D. Genes responsible for apoptosis.
22. The process by which cancer cells spread to distant sites is called:
A. Hyperplasia
B. Dysplasia
C. Invasion
D. Metastasis
23. The "T" in the TNM staging system refers to:
A. Tumor size and local invasion
B. Involvement of lymph Nodes
C. Presence of distant Metastasis
D. Tumor grade
24. Paraneoplastic syndromes are:
A. Direct effects of a tumor mass.
B. Side effects of chemotherapy.
C. Remote effects of cancer not related to metastasis.
D. Infections due to immunosuppression.
