Advanced Pathophysiology Exam 3 NEWEST
QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS) | A+ GRADE
Save
Terms in this set (235)
age
genetic disposition
CAD Risk Factors: Non-
family history
modifiable
ethnic background
gender
Age >55
male
fam hx
personal hx peripheral vasc/Cerebrovascular
disease
smoking
lipid abnorm
CAD risk factors
DM
HTN
obesity
sedentary
cocaine
estrogen use
dyslipidemia - high LDL, low HDL, high triglycerides
becomes oxidized when exposed to endothelial
cells and smooth muscle cell
what happens when LDL
then exposed to macrophages
becomes oxidized
becomes foam cell
makes up atherosclerotic plaque
, reverse cholesterol transport
returns excess cholesterol from the tissue to the
liver where it binds to hepatic receptors and is
what does HDL do
processed or eliminated as bile or converted to
cholesterol-containing steroids
protects LDL from oxidation
lipoproteins can be altered by glycation as a result
explain the relationship of high glucose levels which causes a greater
of lipoprotiens and integration into macrophages (engulf oxidized LDL)
diabetes as a risk factor this then accumulates in the arterial wall causing
for CAD platelet aggregation and smooth muscle
proliferation
excess body fat that is placed predominantly within
the abdomen and upper body, as opposed to the
hips and thighs
android obesity
strongest link with CAD risk r/t insulin resistance,
decreased HDL levels, increased blood pressure,
and inflammation
9 P21 genetic variant associated with a strong risk for CAD
what is the risk of having inverse relationship
an MI in relation to the if you have a parent who had an MI at 40 you have a
age that it occurred in a higher risk than someone who's parent had one at
parent 70
Women typically present false
with CAD symptoms 10
years earlier than men
t/f
nontraditional risk factor
associated with atherosclerosis and thrombosis
lipoprotein (a) and CAD
genetically derived particle
at risk for premature CAD as well as stroke
, acute phase reactant or protein
made in liver
elevated high sensitivity c indirect measure of atherosclerotic plaque-related
reactive protein and CAD inflammation/progression
(hs-CRP) inflammatory marker
the more inflammation the more likely to have
plaque ruptures
t/f lipoproteins increase true
risk for a cardiac event,
thrombus, and stroke
t/f high numbers of large false
and puffy LDL particles high numbers of small dense LDL
are associated with
increased risk for CAD
desirable - <200
total cholesterol levels Borderline - 200-239
high - >240
Optimal: <100
Near optimal: 100-129
LDL levels Borderline high: 130-159
High: 160-189
Very high: >190
desirable - <150
borderline - 150 - 199
Triglycerides levels
high - 200-499
very high - >500
low - <40
HDL levels
high - >60
QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS) | A+ GRADE
Save
Terms in this set (235)
age
genetic disposition
CAD Risk Factors: Non-
family history
modifiable
ethnic background
gender
Age >55
male
fam hx
personal hx peripheral vasc/Cerebrovascular
disease
smoking
lipid abnorm
CAD risk factors
DM
HTN
obesity
sedentary
cocaine
estrogen use
dyslipidemia - high LDL, low HDL, high triglycerides
becomes oxidized when exposed to endothelial
cells and smooth muscle cell
what happens when LDL
then exposed to macrophages
becomes oxidized
becomes foam cell
makes up atherosclerotic plaque
, reverse cholesterol transport
returns excess cholesterol from the tissue to the
liver where it binds to hepatic receptors and is
what does HDL do
processed or eliminated as bile or converted to
cholesterol-containing steroids
protects LDL from oxidation
lipoproteins can be altered by glycation as a result
explain the relationship of high glucose levels which causes a greater
of lipoprotiens and integration into macrophages (engulf oxidized LDL)
diabetes as a risk factor this then accumulates in the arterial wall causing
for CAD platelet aggregation and smooth muscle
proliferation
excess body fat that is placed predominantly within
the abdomen and upper body, as opposed to the
hips and thighs
android obesity
strongest link with CAD risk r/t insulin resistance,
decreased HDL levels, increased blood pressure,
and inflammation
9 P21 genetic variant associated with a strong risk for CAD
what is the risk of having inverse relationship
an MI in relation to the if you have a parent who had an MI at 40 you have a
age that it occurred in a higher risk than someone who's parent had one at
parent 70
Women typically present false
with CAD symptoms 10
years earlier than men
t/f
nontraditional risk factor
associated with atherosclerosis and thrombosis
lipoprotein (a) and CAD
genetically derived particle
at risk for premature CAD as well as stroke
, acute phase reactant or protein
made in liver
elevated high sensitivity c indirect measure of atherosclerotic plaque-related
reactive protein and CAD inflammation/progression
(hs-CRP) inflammatory marker
the more inflammation the more likely to have
plaque ruptures
t/f lipoproteins increase true
risk for a cardiac event,
thrombus, and stroke
t/f high numbers of large false
and puffy LDL particles high numbers of small dense LDL
are associated with
increased risk for CAD
desirable - <200
total cholesterol levels Borderline - 200-239
high - >240
Optimal: <100
Near optimal: 100-129
LDL levels Borderline high: 130-159
High: 160-189
Very high: >190
desirable - <150
borderline - 150 - 199
Triglycerides levels
high - 200-499
very high - >500
low - <40
HDL levels
high - >60
