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RNC-NIC Exam 2025 | Neonatal Intensive Care Certification Practice Test & Study Guide

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Pass the RNC-NIC (Neonatal Intensive Care Nursing) exam. Get the newest 2025 practice test with NCC-aligned questions on pathophysiology, pharmacology, and management of critically ill neonates.

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December 5, 2025
Number of pages
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Written in
2025/2026
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Page 1 of 171


RNC NIC EXAM NEWEST 2025 ACTUAL EXAM|

COMPLETE 150 QUESTIONS AND VERIFIED ANSWERS

(100% CORRECT) ALREADY GRADED A+| RNC NIC

EXAM REVIEW 2025 (NEW!!)

amniocentesis .....ANSWER..... needle puncture of the amniotic sac

to withdraw amniotic fluid for analysis

- screens for chromosomal abnormalities

- typically performed early in 2nd trimester (15-20 wks), more

accurate >20 wks d/t chromosomal presence in fluid

- **also can be used later in pregnancy to assess fetal lung

maturity**

- often recommended for AMA

thrombocytopenia (maternal) .....ANSWER..... - a generally

benign maternal medical complication that is due to hemodilution

(increased RBCs)

,Page 2 of 171


- may be associated with hypertensive conditions r/t pregnancy

- may be associated with s/s of bleeding in the infant

risks of maternal thrombocytopenia .....ANSWER..... can result in:

- increased risk of bleeding in the mother, especially during the

delivery

- **bleeding in the infant (oozing from umbilical cord, prolonged

bleeding from heel sticks, bruising, **petechiae

neonatal petechiae .....ANSWER..... - must consider

hyperbilirubinemia/jaundice (breakdown of RBCs)

- also associated with maternal thrombocytopenia

cytomegalovirus (CMV) .....ANSWER..... - **most common

intrauterine infection**

- transmitted by exposure to infected blood or body fluids

- majority of infants asymptomatic at birth, but 5-15% have later

sequelae (most commonly hearing and vision loss)

,Page 3 of 171


contraindication for breastfeeding .....ANSWER..... - maternal

HIV/AIDS infection

- **HIV/AIDS can be spread through breastfeeding**

signs of HIV in newborn .....ANSWER..... - poor weight gain

- **repeated fungal mouth infections** (thrush)

- enlarged lymph nodes

- enlarged liver/spleen

- neurologic problems

- multiple bacterial infections, including pneumonia

chlamydia .....ANSWER..... - **most common bacterial sexually

transmitted infection**

- *treatment: erythromycin*

signs/symptoms of neonatal chlamydia .....ANSWER..... -

conjunctivitis in first few weeks

, Page 4 of 171


- late-onset: pneumonia at 3-4 months

- otitis media

- gastroenteritis

oligohydramnios .....ANSWER..... - AF volume <1 L at 36 weeks,

<800 mL at term

- can lead to pulmonary hypoplasia d/t amniotic fluid's role in

fetal pulmonary development

- **may be related to Potter sequence/renal agenesis**

because AF is largely made up of fetal urine (no urine if the

baby has no kidneys)

- **can lead to hypoplastic lungs**

- can also lead to IUGR and positional deformities (baby can't

move well)

Potter sequence (renal agenesis) .....ANSWER..... - **Renal

agenesis -> oligohydramnios -> severe pulmonary hypoplasia**
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