N5315 TEST 2 QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) ALREADY GRADED A+
What do CD4/helper T cells do? Ans✓✓✓Activate macrophages, B-
cells, cytotoxic T-cells, and other CD4 cells
What is released by Th1 and what does it do? Ans✓✓✓Releases IL2
and activates cytotoxic Tcells
What does CD4 bind to? Ans✓✓✓MCHII
What is released by Th2 and what does it do? Ans✓✓✓Releases IL4
and binds to B cells and activates them
What does CD8 bind to? Ans✓✓✓MHC1
Humoral immunity involves what cells? Ans✓✓✓B cells
Cell Mediated Immunity involves what cells? Ans✓✓✓T cells
Active acquired immunity Ans✓✓✓results from actual exposure to a
pathogen
Passive acquired immunity Ans✓✓✓Does not involve the host's
immune response. Transferred to recipient
- immediate, short lived immune response
,- only last a few months
Antigen Ans✓✓✓a toxin or other foreign substance that induces an
immune response in the body. Can react with antibodies or antigen
receptors on B and T cells
What do plasma cells do? Ans✓✓✓produce antibodies
IgG Ans✓✓✓-Most common antibody
-Binds with viruses, bacteria, toxins, and macrophages
-Primary antibody in SECONDARY immune response
-Only antibody that crosses placenta
IgE Ans✓✓✓-Binds to mast cells, eosinophils, and basophils
-parasitic infections and hypersensitive reactions
-allergies/allergens
IgM Ans✓✓✓-Main immune globulin produced in early PRIMARY
immune response.
-High levels indicate recent infection
IgA Ans✓✓✓-Main immune globulin found in secretions and mucous
membranes.
-Prevents invaders from attaching to mucous membranes
, IgD Ans✓✓✓-Signals B-cell activation
-Found on the surface of B-lypmhocytes
Mast cells Ans✓✓✓Release histamines, leukotrienes, prostaglandins,
platelet-activating factor, chemotatic factors, and cytokines
Histamine 1 Ans✓✓✓-Promote inflammation
-Found on smooth muscles cells
*broncoconstriction
Histamine Ans✓✓✓-responsible for causing vasodilation
-increases vascular permeability
-increases blood flow to the site of injury
-->erythema and swelling of site
Histamine 2 Ans✓✓✓-Anti-inflammatory; supresses leukocyte
function
-Found in the stomach mucosa, induce secretion of gastic acid
Cytokines Ans✓✓✓-Protein important in cell signaling
-Can be pro/anti inflammatory
Diffuse over short distances, binds to appropriate target cells, and
affects the function of the target cell
ANSWERS (VERIFIED ANSWERS) ALREADY GRADED A+
What do CD4/helper T cells do? Ans✓✓✓Activate macrophages, B-
cells, cytotoxic T-cells, and other CD4 cells
What is released by Th1 and what does it do? Ans✓✓✓Releases IL2
and activates cytotoxic Tcells
What does CD4 bind to? Ans✓✓✓MCHII
What is released by Th2 and what does it do? Ans✓✓✓Releases IL4
and binds to B cells and activates them
What does CD8 bind to? Ans✓✓✓MHC1
Humoral immunity involves what cells? Ans✓✓✓B cells
Cell Mediated Immunity involves what cells? Ans✓✓✓T cells
Active acquired immunity Ans✓✓✓results from actual exposure to a
pathogen
Passive acquired immunity Ans✓✓✓Does not involve the host's
immune response. Transferred to recipient
- immediate, short lived immune response
,- only last a few months
Antigen Ans✓✓✓a toxin or other foreign substance that induces an
immune response in the body. Can react with antibodies or antigen
receptors on B and T cells
What do plasma cells do? Ans✓✓✓produce antibodies
IgG Ans✓✓✓-Most common antibody
-Binds with viruses, bacteria, toxins, and macrophages
-Primary antibody in SECONDARY immune response
-Only antibody that crosses placenta
IgE Ans✓✓✓-Binds to mast cells, eosinophils, and basophils
-parasitic infections and hypersensitive reactions
-allergies/allergens
IgM Ans✓✓✓-Main immune globulin produced in early PRIMARY
immune response.
-High levels indicate recent infection
IgA Ans✓✓✓-Main immune globulin found in secretions and mucous
membranes.
-Prevents invaders from attaching to mucous membranes
, IgD Ans✓✓✓-Signals B-cell activation
-Found on the surface of B-lypmhocytes
Mast cells Ans✓✓✓Release histamines, leukotrienes, prostaglandins,
platelet-activating factor, chemotatic factors, and cytokines
Histamine 1 Ans✓✓✓-Promote inflammation
-Found on smooth muscles cells
*broncoconstriction
Histamine Ans✓✓✓-responsible for causing vasodilation
-increases vascular permeability
-increases blood flow to the site of injury
-->erythema and swelling of site
Histamine 2 Ans✓✓✓-Anti-inflammatory; supresses leukocyte
function
-Found in the stomach mucosa, induce secretion of gastic acid
Cytokines Ans✓✓✓-Protein important in cell signaling
-Can be pro/anti inflammatory
Diffuse over short distances, binds to appropriate target cells, and
affects the function of the target cell
