Test Bank for Basic and Clinical Pharmacology 16th Edition Katzung & Trevor | Complete Chapter Q&A | Nursing & Medical Exam Prep

Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
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,Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
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ChapterY1.YIntroduction:YTheYNatureYofYDrugsY&YDrugYDevelopmentY&YRegulation


1.
AYnurseYworkingYinYradiologyYadministersYiodineYtoYaYpatientYwhoYisYhavi
ngYaYcomputedYtomographyY(CT)Yscan.YTheYnurseYworkingYonYtheYoncologyY
unitYadministersYchemotherapyYtoYpatientsYwhoYhaveYcancer.YAtYtheYPublicYH
ealthYDepartment,YaYnurseYadministersYaYmeasles-mumps-
rubellaY(MMR)YvaccineYtoYaY14-month-
oldYchildYasYaYroutineYimmunization.YWhichYbranchYofYpharmacologyYbestYde
scribesYtheYactionsYofYallYthreeY nurses?
A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

Feedback:

PharmacologyYisYtheYstudyYofYtheYbiologicYeffectsYofYchemicals.YNursesYareYi
nvolvedYwithYclinicalYpharmacologyYorYpharmacotherapeutics,YwhichYisYaYbr
anchYofYpharmacologyYthatYdealsYwithYtheYusesYofYdrugsYtoYtreat,Yprevent,Yan
dYdiagnoseYdisease.YTheYradiologyYnurseYisYadministeringYaYdrugYtoYhelpYdia
gnoseYaYdisease.YTheYoncologyYnurseYisYadministeringYaYdrugYtoYhelpYtreatYaY
disease.YPharmacoeconomicsYincludesYanyYcostsYinvolvedYinYdrugYtherapy.
PharmacodynamicsYinvolvesYhowYaYdrugYaffectsYtheYbodyYandYpharmacokinet
icsYisYhowYtheYbodyYactsYonYtheYbody.


2.
AYphysicianYhasYorderedYintramuscularY(IM)YinjectionsYofYmorphine,YaYna
rcotic,YeveryY4YhoursYasYneededYforYpainYinYaYmotorYvehicleYaccidentYvictim.
YTheYnurseYisYawareYthisYdrugYhasYaYhighYabuseYpotential.YUnderYwhatYcateg

oryYwouldYmorphineYbeYclassified?

,A) ScheduleYI

B) ScheduleYII

C) ScheduleYIII

D) ScheduleYIV

Ans: B

Feedback:

NarcoticsYwithYaYhighYabuseYpotentialYareYclassifiedYasYScheduleYIIYdrugsYb
ecauseYofYsevereYdependenceYliability.YScheduleYIYdrugsYhaveYhighYabuseYp
otentialYandYnoYacceptedYmedicalYuse.YScheduleYIIIYdrugsYhaveYaYlesserYabu
seYpotentialYthanYIIYandYanYacceptedYmedicalYuse.YScheduleYIVYdrugsYhaveYl
owYabuseYpotentialYandYlimitedYdependenceYliability.


3.
WhenYinvolvedYinYphaseYIIIYdrugYevaluationYstudies,YwhatYresponsibili
tiesYwouldYtheYnurseYhave?
A) WorkingYwithYanimalsYwhoYareYgivenYexperimentalY drugs

B) ChoosingYappropriateYpatientsYtoYbeYinvolvedYinYtheYdrugY study

C) MonitoringYandYobservingYpatientsYcloselyYforYadverseY effects

D) ConductingYresearchYtoYdetermineYeffectivenessYofYtheY drug

Ans: C

Feedback:

PhaseYIIIYstudiesYinvolveYuseYofYaYdrugYinYaYvastYclinicalYpopulationYinYwhic
hYpatientsYareYaskedYtoYrecordYanyYsymptomsYtheyYexperienceYwhileYtakingYt
heYdrugs.YNursesYmayYbeYresponsibleYforYhelpingYcollectYandYanalyzeYtheYinf
ormationYtoYbeYsharedYwithYtheYFoodYandYDrugYAdministrationY(FDA)YbutYw
ouldYnotYconductYresearchYindependentlyYbecauseYnursesYdoYnotYprescribeYm
edications.YUseYofYanimalsYinYdrugYtestingYisYdoneYinYtheYpreclinicalYtrials.YS
electYpatientsYwhoYareYinvolvedYinYphaseYIIYstudiesYtoYparticipateYinYstudiesY
whereYtheYparticipantsYhaveYtheYdiseaseYtheYdrugYisYintendedYtoYtreat.YTheseY
patientsYareYmonitoredYcloselyYforYdrugYactionYandYadverseYeffects.YPhaseYIY
studiesYinvolveYhealthyYhumanYvolunteersYwhoYareYusuallyYpaidYforYtheirYpa
rticipation.YNursesYmayYobserveYforYadverseYeffectsYandYtoxicity.

, 4.
WhatYconceptYisYconsideredYwhenYgenericYdrugsYareYsubstitutedYforYbr
andYnameYdrugs?
A) Bioavailability

B) CriticalYconcentration

C) Distribution

D) Half-life

Ans: A

Feedback:

BioavailabilityYisYtheYportionYofYaYdoseYofYaYdrugYthatYreachesYtheYsystemicY
circulationYandYisYavailableYtoYactYonYbodyYcells.YBindersYusedYinYaYgenericY
drugYmayYnotYbeYtheYsameYasYthoseYusedYinYtheYbrandYnameYdrug.YTherefor
e,YtheYwayYtheYbodyYbreaksYdownYandYusesYtheYdrugYmayYdiffer,YwhichYma
yYeliminateYaYgenericYdrugYsubstitution.YCriticalYconcentrationYisYtheYamoun
tYofYaYdrugYthatYisYneededYtoYcauseYaYtherapeuticYeffectYandYshouldYnotYdiffe
rYbetweenYgenericYandYbrandYnameYmedications.YDistributionYisYtheYphaseYo
fYpharmacokinetics,YwhichYinvolvesYtheYmovementYofYaYdrugYtoYtheYbodysYt
issuesYandYisYtheYsameYinYgenericYandYbrandYnameYdrugs.YAYdrugsYhalf-
lifeYisYtheYtimeYitYtakesYforYtheYamountYofYdrugYtoYdecreaseYtoYhalfYtheYpeak
Ylevel,YwhichYshouldYnotYchangeYwhenYsubstitutingYaYgenericY medication.




5.
AYnurseYisYassessingYtheYpatientsYhomeYmedicationYuse.YAfterYlisteningYto
YtheYpatientYlistYcurrentYmedications,YtheYnurseYasksYwhatYpriorityYquestion


?
A) DoYyouYtakeYanyYgenericYmedications?

B) AreYanyYofYtheseYmedicationsYorphanY drugs?

C) AreYtheseYmedicationsYsafeYtoYtakeYduringY pregnancy?

D) DoYyouYtakeYanyYover-the-counterYmedications?

Ans: D

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