BIO 340 Varsani Test 3 Questions and answers with verified solutions 100% correct

BIO 340 VARSANI TEST 3 QUESTIONS AND ANSWERS
WITH VERIFIED SOLUTIONS 100% CORRECT



Agents:



1. Nucleotide base analog



2. Alkylating agent



3. Hydroxylating agent



4. Deaminating agent



5. Oxidizing agent



6. Intercalating agent - correct answer- 1. Transition mutation (AT to
GC or GC to AT)



2. Transition mutation



3. Transition mutation (CG to TA)



4. Transition mutation

,5. Transversion mutation



6. Frameshift mutation



Alkylation damage - correct answer- Donate alkyl group to amino or
keto groups in nucleotides



Alter base-pairing affinity



Ex. Mustard gas



Base analogs - correct answer- mutagenic chemicals



-can substitute for purines or pyrmidines during nucleic acid biosynthesis



-increases tautomeric shifts



Central dogma - correct answer- DNA-->RNA-->protein



-DNA is a template for RNA synthesis (transcription)

, -RNA is template for proteins synthesis (translation)



-it is conserved in all cellular forms of life



DNA info is replicated by replication and is passed on to the next
gerneration



Chargaff's Rules - correct answer- 1. 4 nucleotide NOT present in
equal amounts



2. Variation between species



3. # A=T and G=C



4. Percentage of C+G does not equal percentage of A+T



5. The ratio of purines and pyrimidines was always ~1



Chemical mutagens - correct answer- Nitrous acid (C --> U and A-->
hypo)



Nitrosoamines (demamination of A and C)