USMLE Step 1 Questions and Answers Graded A+

USMLE Step 1 Questions and Answers
Graded A+

Hormone to test for menopause. - Correct answer-high FSH

Treatment of Heparin Induced Thrombocytopenia - Correct answer-Direct

thrombin inhibitors-Agatroban

Then protamine sulfate

PT or PTT for Heparin - Correct answer-PTT

PT or PTT for Warfarin - Correct answer-PT

Skin necrosis from warfarin, what do you do? - Correct answer-Give heparin

Antidote to excessive thrombolytics - Correct answer-Aminocaproic acid

Glanzmanns Thrombasthenia - Correct answer-GPIIb/IIIa- platelet adhesion

Bernard soulier - Correct answer-Gp1b

Aspirin decreases platelet adehsion, activation or aggregation? - Correct answer-

Activation



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, Drugs that decrease platelet activation - Correct answer-aspirin, toclopidine,

clopidogrel- block ADP receptors

Drugs that decrease aggregation - Correct answer-abciximab, eptifibatide, tirofiban

Why do sulfonamides decrease increase PT in patients on warfarin? - Correct

answer-Sulfonamides displace the weakly but extensively bound warfarin on

plasma proteins. This is different mechanism from cimetidine which increase P450

Onset, peak effect and duration of lispro - Correct answer-onset: 0.3-0.5hrs

peak effect: 1-2 hrs

duration: 2-4hrs

Onset peak effect and duration of regular - Correct answer-onset: 0.5-1hrs

peak effect: 2-4hrs

duration: 5-7hrs

Onset, peak effect and duration of glargine - Correct answer-onset: 1hr

peak effect: no peak

duration>24hrs

What increases insulin release? what decreases insulin release - Correct answer-1.

glucose, amino acids, sulfonylureas, M-agonists, B2 agonists 2. a2 agonists

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