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NR507- Advanced Pathophysiology Final Exam/2025/2026

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NR507- Advanced Pathophysiology Final Exam/2025/2026

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November 29, 2025
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NR507- Advanced Pathophysiology
Final Exam 100% Fully Updated



Acute renal failure Correct Answers Reversible

Determining prognosis- kidneys respond to diuretic with good output; this indicates that kidneys are
functioning well



Acute Pyelonephritis Correct Answers Diagnosing by clinical symptoms alone can be difficult; can be
similar to cystitis



Diagnosis established by:

-Urine culture

-Urinalysis (WBC casts indicates pyelonephritis, but may not always be present)

-Signs/Symptoms

-Complicated pyelonephritis requires blood cultures and urinary tract imaging



Renal Calculi (Renal Stones) Correct Answers Goals of Treatment:

Manage acute pain

Promote passage of stone

Reduce size of stone

Prevent new stone formation



Chronic Renal Failure Correct Answers Chronic Kidney Disease (CKD) is a progressive loss of renal
function associated with systemic disease such as hypertension, diabetes mellitus (most significant risk
factor), systemic lupus erythematosus or intrinsic kidney disease

CKD stage is determined by estimates of GFR and albuminuria

, Who is a candidate for dialysis? Correct Answers End-stage renal disease (ESRD) is the final stage of CKD
with the number one cause being diabetes mellitus combined with hypertension. At this point, the
patient is completely dependent on dialysis to survive.

CKD is classified into five stages and is based on the patient's GFR rather than symptoms.



Patients will need dialysis when the following symptoms are present:

--Metabolic acidosis.

--Hyperkalemia: Hyperkalemia in the presence of EKG changes (peaked T-waves) is an indication for
dialysis. --Hyperkalemia by itself is not an indication for dialysis.

--Drug toxicity: Drug toxicity due to the following drugs is an indication for dialysis and include
salicylates, Lithium, Isopropanol, Methanol and Ethylene glycol).

--Fluid volume overload that is not responsive to diuretics.

--Uremic symptoms due to nitrogenous wastes in the blood stream.



Stage I CKD Correct Answers There is kidney damage with normal or elevated GFR

90-120



Stage II CKD Correct Answers There is kidney damage with mild decrease in GFR

60-89



Stage III CKD Correct Answers There is a moderate decrease in GFR

30-59



Stage IV CKD Correct Answers There is a severe decrease in GFR

15-29



Stage V CKD Correct Answers Kidney failure- End-stage renal disease

<15 (dialysis) Once Stage IV is reached, progression to Stage V is inevitable as well as dialysis or kidney
transplant
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