VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
PART I — NGN-STYLE CASE STUDIES (QUESTIONS 1–25)
===============================
📘 CASE STUDY 1 — COPD EXACERBATION (Questions 1–5)
Patient: 67-year-old male with COPD.
Meds: Methylprednisolone IV, albuterol nebulizer, tiotropium,
azithromycin.
1. (Matrix: Match drug → expected action)
Methylprednisolone →
Albuterol →
Tiotropium →
Azithromycin →
Actions:
A. Long-acting bronchodilation
B. Reduces airway inflammation
C. Kills bacteria
D. Rapid bronchodilation
Answer:
,VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
Methylprednisolone → B
Albuterol → D
Tiotropium → A
Azithromycin → C
Rationale: Steroids reduce inflammation; albuterol works quickly;
tiotropium is long-acting; azithromycin is an antibiotic.
2. (Multiple-response)
Which findings show albuterol is working?
A. Wheezing decreases
B. RR improves
C. HR decreases
D. O₂ sat increases
E. Cough decreases
Answer: A, B, D
Rationale: Bronchodilation improves air movement, respiratory
rate, and oxygenation.
,VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
3 (Cloze)
A major adverse effect of high-dose steroids is __________.
Answer: Hyperglycemia
Rationale: Steroids elevate blood glucose.
4.
Which symptom must be reported when taking tiotropium?
A. Dry mouth
B. Blurred vision
C. Cough
D. Increased appetite
Answer: B
Rationale: Indicates possible anticholinergic toxicity.
5 (Priority)
Which new finding requires immediate intervention?
A. Thick sputum
B. HR 118
, VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
C. O₂ sat 84%
D. Mild tremors
Answer: C
Rationale: Severe hypoxia is priority.
📘 CASE STUDY 2 — STROKE + BLOOD PRESSURE CONTROL
(Questions 6–10)
Meds: Labetalol IV, alteplase recently completed, aspirin.
6. (Matrix: Expected vs. Unexpected)
Findings:
BP 190/110
HR 56
New headache
No bleeding
Nausea
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
PART I — NGN-STYLE CASE STUDIES (QUESTIONS 1–25)
===============================
📘 CASE STUDY 1 — COPD EXACERBATION (Questions 1–5)
Patient: 67-year-old male with COPD.
Meds: Methylprednisolone IV, albuterol nebulizer, tiotropium,
azithromycin.
1. (Matrix: Match drug → expected action)
Methylprednisolone →
Albuterol →
Tiotropium →
Azithromycin →
Actions:
A. Long-acting bronchodilation
B. Reduces airway inflammation
C. Kills bacteria
D. Rapid bronchodilation
Answer:
,VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
Methylprednisolone → B
Albuterol → D
Tiotropium → A
Azithromycin → C
Rationale: Steroids reduce inflammation; albuterol works quickly;
tiotropium is long-acting; azithromycin is an antibiotic.
2. (Multiple-response)
Which findings show albuterol is working?
A. Wheezing decreases
B. RR improves
C. HR decreases
D. O₂ sat increases
E. Cough decreases
Answer: A, B, D
Rationale: Bronchodilation improves air movement, respiratory
rate, and oxygenation.
,VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
3 (Cloze)
A major adverse effect of high-dose steroids is __________.
Answer: Hyperglycemia
Rationale: Steroids elevate blood glucose.
4.
Which symptom must be reported when taking tiotropium?
A. Dry mouth
B. Blurred vision
C. Cough
D. Increased appetite
Answer: B
Rationale: Indicates possible anticholinergic toxicity.
5 (Priority)
Which new finding requires immediate intervention?
A. Thick sputum
B. HR 118
, VERSION 4 — HESI + NGN PHARMACOLOGY PRACTICE EXAM
100 ORIGINAL QUESTIONS + ANSWERS + RATIONALES
C. O₂ sat 84%
D. Mild tremors
Answer: C
Rationale: Severe hypoxia is priority.
📘 CASE STUDY 2 — STROKE + BLOOD PRESSURE CONTROL
(Questions 6–10)
Meds: Labetalol IV, alteplase recently completed, aspirin.
6. (Matrix: Expected vs. Unexpected)
Findings:
BP 190/110
HR 56
New headache
No bleeding
Nausea
