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NR507 HEMATOLOGIC DISORDERS| QUESTIONS AND ANSWERS VERIFIED| GUARANTEED PASS| LATEST UPDATE 2025/2026

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NR507 HEMATOLOGIC DISORDERS| QUESTIONS AND ANSWERS VERIFIED| GUARANTEED PASS| LATEST UPDATE 2025/2026

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NR507 HEMATOLOGIC DISORDERS| QUESTIONS AND ANSWERS
VERIFIED| GUARANTEED PASS| LATEST UPDATE 2025/2026




the site of blood cell formation hematopoiesis varies with age -CORRECT
ANSWER -fetus - yolk sac beginning 3rd week gestation; shift to fetal liver &
spleen by week 8 and to bone marrow by 5 month


-birth to 5 years red marrow of all bones make blood cells


-after 20 years red marrow primarily located in ilium, vertebrae, cranium and
jaw, sternum and ribs, humerous and femur.


Hematopoiesis occurs throughout life and is stimulated by -CORRECT
ANSWER infiltration of the yellow or fatty bone marrow with red bone
marrow cells.


faster proliferation and differentiation of stem and daughter cells.


Hematopoietic stem cells are -CORRECT ANSWER -are progenitors (apart
of) of all hematological cells.


-proliferate and differentiate under the control of numerous growth factors and
cytokinis to form the three types of cells found in peripheral blood: RBCs,
WBCs, and platelets


Erythropoiesis -CORRECT ANSWER formation of red blood cells:

, -The growth factor erythropoietin is made by the kidney and to a very small
extent in the liver in response to tissue hypoxia


-is also stimulated by androgens (testosterones)


-Normal red blood cell level is between 4.2 to 6.2 million cells per cubic
millimeter (approximately 45% of blood volume)


-able to replenish 1% of circulating red blood cell mass every 24 hours, which is
equivalent to 2.5 million red blood cell synthesized per second.


The mature RBC structure -CORRECT ANSWER biconcave spherical disk for
maximum surface area for gas exchange


reversible deformability to squeeze through capillaries


lacks a nucleus, ribosome, mitochondria ( Without these structures, red blood
cells cannot divide or do protein synthesis and can only perform anaerobic
metabolism,


lifespan in circulation is approximately 100-120 days (But in that time frame, it
will have traveled thousands of miles to our vascular system)


Red blood cells are essentially a sack of hemoglobin. -CORRECT ANSWER
It is estimated that there are approximately 300 million hemoglobin molecules
per red blood cell. Hemoglobin makes up 90% of the dry weight of the cell.


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