PATHOPHYSIOLOGY QUESTIONS
AND ANSWERS
What bis banxiety? b- bcorrect banswer✔✔Unpleasant bemotion bcommonly bcaused bby
bperception bof bactual bor bpotential b(anticipatory) bdanger bthat bthreatens bthe bsecurity
bof bthe bindividual
• bAffects bhow byou bTHINK, bFEEL band bACT
What bcan buncontrolled banxiety blead bto? b- bcorrect banswer✔✔functional bimpairment
Abnormal bstress bresponse b- bcorrect banswer✔✔• bDisproportional bresponse bleading
bto birrational bfear bthat bimpairs bdaily bfunctioning b
• bResponse bis bexcessive, bpersistent, band bmeets bDSM-V bcriteria
Risk bof bsuicide bin banxiety bdisorders b- bcorrect banswer✔✔Significant bincreased brisk
bin bsuicide b- b2x b- bEspecially bPanic bDisorder, bPTSD band bGAD
What bis bthe bMost bcommon bpsychiatric billness? b- bcorrect banswer✔✔anxiety
• bOnset btypically bbefore bage b30 b
• bLife-time bprevalence b~25%
Common bRisk bFactors bfor bAnxiety band bRelated bDisorders b- bcorrect banswer✔✔•
bSubstance bAbuse bDisorder b(SUD) b
• bFamily bhistory b- bgenetic bpredisposition b
• bPersonal bhistory bof banxiety, bmood bdisorder bor bADHD b
• bChildhood bstressful blife bevents bor btrauma b
• bEnvironmental bstressors b- bE.g. bdeath, bdivorce, bisolation b(poor bsocial bsupport),
bpoverty, bunemployment b
• bBeing bfemale b
• bChronic bmedical billness
Which bantibiotics bare bassociated? b- bcorrect banswer✔✔quinolones b(ciprofloxacin),
bisoniazid
, Psyciatric bcauses b- bcorrect banswer✔✔Mood bdisorder, bsubstance babuse,
bpersonality bdisorders
Neurologic bcauses b- bcorrect banswer✔✔seizure, bstroke, bmigraine
CV bcauses b- bcorrect banswer✔✔Angina, barrhythmias, bmyocardial binfarction
endocrine/metabolic bcauses b- bcorrect banswer✔✔Hypo/hyperthyroid, bhypoglycemia,
bpheochromocytoma, bCushing's bDisease, bhyponatremia, bhyperkalemia
Resp bcauses b- bcorrect banswer✔✔Asthma, bCOPD, bhyperventilation
Is banxiety busually bpresent bby bitself? b- bcorrect banswer✔✔- bMore bthan bhalf bof
bpatients bwith ban banxiety bdisorder bhave bmultiple banxiety bdisorders
- bAnxiety bis boften bcomorbid bwith bother bpsychiatric bdisorders:
Anxiety bphysical bS/Sx b- bcorrect banswer✔✔• bCNS b- bInsomnia, b"light bheadedness",
bloss bof benergy, bheadache, bfatigue, bflushing, bchills b
• bCV- bPalpitations, bchest bpains b
• bRESP b- bShortness bof bbreath, bchoking bsensation b
• bMSK/DERM b- bSweating, bmuscle btension, btremors, bshaking b
• bGI b- bNausea, bloss bof bappetite, bdiarrhea, b"butterflies" bin bstomach, bstomach bpain b
• bGU b- bBladder bweakness
Psychological bS/Sx b- bcorrect banswer✔✔• bFear b
• bWorry b(>50%) b
• bIndecision b
• bApprehension b
• bEasily bstartled b
• bRestlessness b
• bIrritability b
• bPoor bConcentration
Functional bS/Sx b- bcorrect banswer✔✔• b↓Productivity b
• bSocial bisolation b
• bPoor bcoping bskills
All banxiety bdisorders bhave bwhat b2 boverlapping bsymptoms? b- bcorrect
banswer✔✔Fear bcoupled bwith bworry
b• bFear b= bpanic, bphobia
b• bWorry b= banxious bmisery, bapprehensive bmisery, bobsessions
GAD bPhysical bmanifestations b- bcorrect banswer✔✔• bDizziness, bdecreased bsex
bdrive, birritable b
• bIncreased bmuscle btension b