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Samenvatting Hoorcollege Psoriasis en ichtyosis

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Psoriasis en ichtyosis

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November 27, 2025
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2024/2025
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Psoriasis en ichtyosis

Inhoudsopgave
Psoriasis en ichtyosis.....................................................................................1
Psoriasis.............................................................................................................................. 2
Histopathologie van psoriasis.............................................................................................3
Voorkeurplaatsen van psoriasis........................................................................................... 3
Oorzaken psoriasis.............................................................................................................. 4
Vormen van psoriasis.......................................................................................................... 4
1.Psoriasis vulgaris............................................................................................................. 5
2.Psoriasis guttata.............................................................................................................. 5
3.Psoriasis annularis (ringvormig).......................................................................................6
4.Psoriasis inversa (in de plooien).......................................................................................6
5.Psoriasis unguium (nagel psoriasis).................................................................................6
6.Psoriasis palmoplantaris (handpalmen, voetzolen)..........................................................7
7.Psoriasis erytrodermi....................................................................................................... 7
8.Psoriasis pustulosa........................................................................................................... 8
9.Psoriasis arthropathica (met ontsteking van de gewrichten)...........................................9
Co-morbiditeiten bij psoriasis: multi- systeemziekte...........................................................9
Behandeling psoriasis....................................................................................................... 10
1.Lokale behandeling:....................................................................................................... 10
2.Behandeling met bestraling:.......................................................................................... 10
3.Systemische behandeling (altijd 2e lijn).........................................................................10
Take home message......................................................................................................... 10
Ichtyosis............................................................................................................................ 11
1.Ichthyosis vulgaris......................................................................................................... 11
Aetiologie/ ontstaanswijze:............................................................................................... 11
Diagnostiek....................................................................................................................... 12
Therapie............................................................................................................................ 12
2.Steroïd sulfatase deficiëntie........................................................................................... 12
Diagnostiek....................................................................................................................... 13
Behandeling en prognose................................................................................................. 13

, Psoriasis
Een erythematosquameuze dermatose, maar ook een systeemziekte (niet
besmettelijk)

 Wat is psoriasis:
o Psoriasis is een veelvoorkomende (systemische) huidaandoening die
gepaard gaat met steriele ontsteking en versnelde celdeling in de
huid,
waarbij zowel erfelijke als omgevingsfactoren een belangrijke rol
spelen
 Karakteristieke afwijkingen bij psoriasis
o Scherp begrensde rode, zilverwit schilferende verheven plaques,
vooral op de strekzijde van armen en benen, op de stuit en op het
behaarde hoofd. De ziekte kan sterk variëren in duur, frequentie van
verergering en uitbreiding




- Links normale huid
- Rechts psoriasis: gestoorde uitrijping
- Psoriasis wordt gekenmerkt door een
stoornis in
de groei van de huid (epidermis)
- Aanmaak huidcellen 5-6 dagen i.p.v. 26-27
dagen
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