QUESTIONS AND CORRECT ANSWERS
Hypothyroidism Causes - CORRECT ANSWERS✅✅Gland malfunction
Pituitary tumor
Removal of gland
iodine deficiency
Hypothyroidism S/Sx - CORRECT ANSWERS✅✅tired
poor memory
dry skin
brittle hair and nails
bradycardia
constipation
heavy menses
cold intolerant
weight gain
Levothyroxine (Synthyroid) - CORRECT ANSWERS✅✅MOA: synthetic T4 converted to
T3
Food interferes with absorption (esp. Ca)
Very highly protein bound= long T 1/2
Safe in pregnancy
Levothyroxine Adverse Effects - CORRECT ANSWERS✅✅Rare if TSH in therapeutic
range
OD is thyrotoxic crisis
-hyperthermia
-tachycardia
-restlessness
-tremor
,-weight loss
Levothyroxine Pt Education - CORRECT ANSWERS✅✅Take early AM on empty stomach
Generic/brand consistency
Regular lab monitoring
Report thyrotoxic symptoms
Hyperthyroidism Causes - CORRECT ANSWERS✅✅Grave's Disease
Toxic nodular goiter
Hyperthyroidism S/Sx - CORRECT ANSWERS✅✅anxious
poor concentration
hungry
tachycardia
chest pain
hyper defecation
irregular to no menses
heat intolerance
weight loss
Methimazole & Propylthiouracil (PTU) - CORRECT ANSWERS✅✅MOA: inhibit thyroid
hormone synthesis
PTU also suppresses conversion of T4 to T3 in the body
PTU preferred in pregnancy
Methimazole & Propylthiouracil (PTU) Adverse Effects - CORRECT
ANSWERS✅✅Teratogenic (methimazole)
Too much can cause hypothyroidism
Pt Education: frequent lab monitoring required
, Glucocorticoids Physiologic Levels - CORRECT ANSWERS✅✅Minimal adverse effects
-glucose for the brain
-protein metabolism
-fat metabolism
-keeps BP in check
-maintains blood cells
Glucocorticoids Pharmacologic Levels - CORRECT ANSWERS✅✅Higher risk of adverse
effects
Treating other conditions:
-allergic rxns
-lung conditions
-inflammation
-dermatologic conditions
Addison's Disease` - CORRECT ANSWERS✅✅Not enough hormone
Requires lifelong supplementation with glucocorticoid
Needs extra steroid dose during times of physical stress (fever, illness, surgery, trauma)
Addison's Disease S/Sx - CORRECT ANSWERS✅✅Bronzed skin (increase melatonin
synthesis)
Hypoglycemia (glucocorticoid deficiency)
Orthostatic hypotension (volume depletion)
Weight loss ( loss of appetite & dehydration)
GI upset (N/V/D)
Weakness & fatigue
Adrenal Crisis - CORRECT ANSWERS✅✅- Profound fatigue
- Dehydration
- Vascular collapse (low bp)
- Renal shut down