PATHOPHYSIOLOGY 9TH EDITION McCANCE ALL CHAPTERS 1-50 QUESTIONS & ANSWERS 2025 TEST BANK

TEST BANK FOR PATHOPHYSIOLOGY 9TH
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x6 EDITION McCANCE ALL CHAPTERS 1-50
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x6 QUESTIONS & ANSWERS 2025.
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,Chapter1-49 6
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Chapter01: Cellular Biologyx6 x6 x6




Rogers:McCance& Huether’sPathophysiology, 9thEdition
6
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MULTIPLE CHOICE x6




1. Which statement best describes the cellular function of metabolic absorption?
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a. Cells can produce proteins. x6 x6 x6




b. Cells can secrete digestive x6 x6 x6




enzymes. x6




c. Cells can take in and use x6 x6 x6 x6 x6




nutrients. x6




d. Cells can synthesize fats. x6 x6 x6




ANS: x 6 C
In metabolic absorption, all cells take in and use nutrients and other substances
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from their surroundings. The remaining options are not inclusive in their
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descriptions of cellular metabolic absorption.
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DIF: Cognitive Level: Remembering x6 x6




2. Whereis most of a cell’s genetic information, including RNA and DNA, contained?
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a. Mitochond
ria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: x 6 C
The nucleus contains the nucleolus, a small dense structure composed largely
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of RNA, most of the cellular DNA, and the DNA-binding proteins, such as the
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histones, which regulate its activity. The mitochondria are responsible for
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cellular respiration and energy production.
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Ribosomes’ chieffunction is to provide sites for cellularprotein synthesis. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6




Lysosomes function as the intracellular digestive system.
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DIF: Cognitive Level: Remembering x6 x6




3. Which component of the cell produces hydrogen peroxide (H2O2) byusing
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oxygen to remove hydrogen atoms from specific substrates in an oxidative
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reaction?
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a. Lysosome
s
b. Peroxisom
es
c. Ribosome

, s
d. Endosome
ANS: x 6 B

, Peroxisomes are so named because they usually contain enzymes that use oxygen to
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remove hydrogen atoms from specific substrates in an oxidative reaction that produces
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H2O2, which is a powerful oxidant and potentially destructive if it accumulates or
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escapes from peroxisomes. Ribosomes are RNA-protein complexes (nucleoproteins)
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that are synthesized in the nucleolus and secreted into the cytoplasm through pores in
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the nuclear envelope called nuclear pore complexes. Lysosomes are saclike structures
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that originate from the Golgi complex and contain more than 40 digestive enzymes
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called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
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carbohydrates. An endosome is a vesical that has been pinched off from the cellular
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membrane.
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DIF: Cognitive Level: Remembering x6 x6




4. Which cell component is capable of cellular autodigestion when it is
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released during cell injury?
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a. Ribosome
b. Golgi complex x6




c. Smooth endoplasmic x6




reticulum
x6




d. Lysosomes
ANS: x 6 D
Thelysosomal membrane acts as a protective shield between the powerful
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digestive enzymes within the lysosome and the cytoplasm, preventing their
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leakage into the cytoplasmic matrix. Disruption of the membrane by various
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treatments or cellular injury leads to a release of the lysosomal enzymes,
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which can then react with their specific substrates, causing cellular self-
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digestion. The chief function of a ribosome is to provide sites for cellular
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protein synthesis. The Golgi complex is a network of flattened, smooth
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vesicles and membranes often located near the cell nucleus. The smooth
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endoplasmic reticulum is involved in steroid hormone production and
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removing toxic substances from the cell.
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DIF: Cognitive Level: Remembering x6 x6




5. Which cAMP-mediated response is related to antidiuretic hormone?
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a. Increased heart rate and force of x6 x6 x6 x6 x6




contraction
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b. Secretion of cortisol x6 x6




c. Increased retention of water x6 x6 x6




d. Breakdown of fat x6 x6




ANS: x 6 C
Antidiuretic hormone leads to increased retention of water in the body. x6 x6 x6 x6 x6 x6 x6 x6 x6 x6




Epinephrine causes increases in heart rate and force of contraction. Increased
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cortisol secretion is due to ACTH. Breakdown of fat is due to glucagon.
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DIF: Cognitive Level: Remembering x6 x6




6. During which phase of the cell cycle is DNA synthesized?
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