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Unit 3 (Part 2) – Central & Peripheral Nervous System, Senses, and Integration

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Part 2 dives deeper into the central and peripheral nervous systems, the autonomic branches, and special sensory physiology. These notes explain the brain’s major structures, reflex pathways, and sensory mechanisms with the clarity and color that Silverthorn’s chapters are known for. This set builds on Unit 3 (Part 1) and is ideal for mastering CNS anatomy, somatic and autonomic function, and sensory signal transduction.

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Uploaded on
November 26, 2025
Number of pages
9
Written in
2024/2025
Type
Class notes
Professor(s)
Law
Contains
All classes

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Spinal Nerves of CNS
Structural
·
Separation section of spinal nerve
Iransverse
> covers each axon
Endoneurium -




microm
-




·
-

Perineurium-> covers a fascicle (collection of axons

Epineurium -
> covers nerve
-




·
Roots (2 each
Dorsal root-sensory only ; includes dorsal root ganglia
-




-

Ventral (anterior) root -
> motor axons only

central
canal




org
dorsal
·




(ascending)tracts
* blue :
sensory
pred motor :

(descending) tracts

Clinical procedures
·
Epidural
epidural space :
between duras the periosteum (membrane
covering vertebral
-




-
to obtain CSF need to enter the subdural space
I

, CNS
·
Parts of the brain
-

Brainstem

Cerebellum
-




Diencephalon
-




Cerebrum
-




·

meninges > same as
-
spinal cord except :




-

Dura mater is 2
layers' forms the venous sinuses between the layers
-no epidural space

Cerebrospinal Fluid
·
surrounds brains spinal cord within subarachnoid space

produced by choroid plexus in third ventricle
-




-returns to plasma by arachnoid villi

contiguous with cerebral interstitial fluid
-




lonic constituents similar to plasma more
regulated
·
,



· Doesn't contain formed bodies (RBCs,immune
:
, platelets) large proteins
ofxn >
-
protect from external influences (Chem composition changes) physical protection
.
,



Blood-Brain Barrier
·

highly selective permeability of brain capillaries prevents most filtration,inclu . water
-


protects CSF from large fluctuations in -> water-soluble compounds/toxins pressure
Neural Tissue Metabolism
·
Oxygen/Carbon dioxide -
>
passes freely across BBB

Glucose primary metabolic fuel for (responsible for50% total body glucose usage)
· -
neurons

membrane transporters glocuse from plasma into brain interstitial fluid
-


move

-



progressive hypoglycemia leads to confusion unconsciousness, death
,




Spinal Lord
organization
segments
·




-
> Dorsal horns (viscerals somatic
Grey matter - sensory nuclei) ,
lateral horns (visceral motor nuclei) Ventral horns (somatic motor)
,



-
white matter -
> Divided into columns
of tracts
Ascending tracts sensory info from body to brain
· :




Descending tracts motor
signal from brain to body parts
· :




Propriospinal tracts axons of
·
:
neurons that originate send in the cord

segments associated with spinal nerves
·
>
- each nerve branches into 2 roots

-

dorsal root neurons carry sensory info

dorsal root
ganglia contain afferent (sensory) nuclei
·




·
afferent neurons connect with interneurous in dorsal horn

-

ventual roots carry efferent (motor) signals from the CNS to body parts
·
Spinal reflexes integrated in the spinal cord
:




-
> inborn (stretch tendon pain) learned
fxn - , ,



-

level of integration spinal >
-
,
cranial
-

components+ > sensory receptor, afferent neuron ,
integration center, efferent neuron , effector
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