NUR 651 Exam 3 Questions With
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Already graded A+|latest Release
Children's Dosing is most often calculated as?
mg/kg
Drug extrahepatic metabolism may be impaired by?
grapefruit juice
Herbal supplements taken with anticoagulants increases?
bleeding risk
The need for dosage adjustment for drugs renally cleared occurs
once the patient's creatinine clearance is?
50 mL/hr
What is the basis for accurate dosing of antineoplastic drugs?
body surface area
What is the effect of smoking on liver metabolism?
increase liver metabolism
The Joint Commission's "Do Not Use" list of medical abbreviations
does not apply to?
preprogrammed health information technology systems
The FDA's Med Watch Program applies to?
ADRs from clinical practices
GI surface area is greater in children or adults?
Children when compared to adults
Preferred dosage form for pediatric patients?
liquids
What medication is used for constipation?
Docusate (colace)
What medication is indicated for nausea?
Promethazine (Phenergan)
What is the mechanism of action of Esomeprazole (nexium)?
proton pump inhibitor
What is indicated for GERD?
Omeprazole (prilosec)
What medication can cause GERD?
Aspirin
Ondansetron (Zofran) is?
,a serotonin antagonist
How do bulk laxatives act on constipation?
absorbing water and expanding creating peristalsis with increased pressure
What is Linaclotide (Linzess) indicated to treat?
constipation
Promethazine (Phenergan) should be used with caution in patients
who have what disease?
Parkinson's disease
What does Ketoconzole require in the body in order to be properly
absorbed?
low pH in the stomach
What is Zolpidem (Ambien) indicated for?
Insomnia
What is the function of carbidopa?
Inhibit metabolism of levodopa OUTSIDE of the CNS
What is Ropinirole (requip) indicated for?
Parkinson's disease
What is the mechanism of action of Ropinirole (Reuip?
bind to dopamine receptors
What class is Gabapentin (Neurontin)
calcium channel blocker
What is Escitalopram (lexapro) indicated for?
depression
What does DUloxetine (Cymbalta) do?
Reuptake inhibitor of serotonin and norepinephrine
What effects do tricyclic antidepressants have?
cardiotoxic effects
What is Baclofen indicated for?
spasticity
What is the mechanism of action of Valproic acid (Depakote)?
sodium channel inhibitor
Beta blockers act on the kidneys to decrease what?
renin release
Ace inhibitors producea more profound decrease in blood pressures
than angiotensin receptor antagonist because?
they decrease concentration of angiotensin II
What is an adverse reaction of ACE inhibitors?
cough
The heart pumps more efficiently when the patient is on digoxin
because the drug does what?
,Increases force of contraction and decreases the rate of contraction
What class of antibiotics are used with caution in patients that take
statins?
Erythromycins
Ezetimibe (Zetia) mechanism does what?
cholesterol absorption inhibitor
How does Gemfibrozil (Lopid) controls the synthesis of lipoprotein
metabolzing enzymes?
Binds to a DNA transcription regulator
Compelling indications for an ACE inhibitor as treatment for
hypertension based on clinical trials includes:
1. Pregnancy
2. Renal parenchymal disease
3. Stable angina
4. Dyslipidemia
Renal parenchymal disease
ACE inhibitors are the drug of choice for treating hypertension in
diabetic patients because they:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
What does the provider understand about the issue of diabetic renal
protection with ACE? Diabetic patients:
Have a reduced rate of renal progression but still need to be discontinued
when advanced renal issues present.
Angioedema: a potentially life-threatening adverse response to ace
inhibitors is angioedema. Which of the following is true about this
adverse reaction?
Swelling of the tongue or hoarseness are the most common symptoms
Prior to developing a plan for the treatment of asthma, the patient's
asthma should be classified according to the NHLBI Expert Panel 3
guidelines. In adults mild-persistent asthma is classified as asthma
symptoms that occur:
1. Daily
2. Daily and limit physical activity
3. Less than twice a week
, 4. More than twice a week and less than once a day
More than twice a week and less than once a day
One goal of asthma therapy outlined by the NHLBI Expert Panel 3
guidelines is:
1. Ability to use albuterol daily to control symptoms
2. Minimize exacerbations to once a month
3. Keep nighttime symptoms at a maximum of twice a week
4. Require infrequent use of beta 2 agonists (albuterol) for relief of
symptoms
Require infrequent use of beta 2 agonists for relief of symptoms
Asthma exacerbations at home are managed by:
Increasing the frequency of beta 2 agonists and contacting their provider
One goal of asthma management in children is:
1. They independently manage their asthma
2. Participation in school and sports activities
3. No exacerbations
4. Minimal use of inhaled corticosteroids
Participation in school and sports activities
Pregnant patients with asthma may safely use throughout their
pregnancy:
Inhaled corticosteroids (budesonide)
Martin, a 60-year-old patient with hypertension, first line decongestant
to prescribe would be:
Nasal oxymetazoline
Education for patients who use inhaled beta agonists and inhaled
corticosteroids include:
Use the inhaled beta 2 agonists first followed by inhaled corticosteroids
What medication is used in CHF?
Spironolactone
Nitrate acts on the heart to do what?
decrease workload by reducing preload
What calcium channel blocker can be used with a beta blocker?
Amlodipine (Norvasc)
Why do calcium channel blockers have different tissue selectivity?
They bind to calcium channels in different tissues
What is recommended therapy for intermittent asthma?
short acting beta agonist
What is the mechanism of action of albuterol (Proventil)?
Complete Solutions|Sure To Pass|
Already graded A+|latest Release
Children's Dosing is most often calculated as?
mg/kg
Drug extrahepatic metabolism may be impaired by?
grapefruit juice
Herbal supplements taken with anticoagulants increases?
bleeding risk
The need for dosage adjustment for drugs renally cleared occurs
once the patient's creatinine clearance is?
50 mL/hr
What is the basis for accurate dosing of antineoplastic drugs?
body surface area
What is the effect of smoking on liver metabolism?
increase liver metabolism
The Joint Commission's "Do Not Use" list of medical abbreviations
does not apply to?
preprogrammed health information technology systems
The FDA's Med Watch Program applies to?
ADRs from clinical practices
GI surface area is greater in children or adults?
Children when compared to adults
Preferred dosage form for pediatric patients?
liquids
What medication is used for constipation?
Docusate (colace)
What medication is indicated for nausea?
Promethazine (Phenergan)
What is the mechanism of action of Esomeprazole (nexium)?
proton pump inhibitor
What is indicated for GERD?
Omeprazole (prilosec)
What medication can cause GERD?
Aspirin
Ondansetron (Zofran) is?
,a serotonin antagonist
How do bulk laxatives act on constipation?
absorbing water and expanding creating peristalsis with increased pressure
What is Linaclotide (Linzess) indicated to treat?
constipation
Promethazine (Phenergan) should be used with caution in patients
who have what disease?
Parkinson's disease
What does Ketoconzole require in the body in order to be properly
absorbed?
low pH in the stomach
What is Zolpidem (Ambien) indicated for?
Insomnia
What is the function of carbidopa?
Inhibit metabolism of levodopa OUTSIDE of the CNS
What is Ropinirole (requip) indicated for?
Parkinson's disease
What is the mechanism of action of Ropinirole (Reuip?
bind to dopamine receptors
What class is Gabapentin (Neurontin)
calcium channel blocker
What is Escitalopram (lexapro) indicated for?
depression
What does DUloxetine (Cymbalta) do?
Reuptake inhibitor of serotonin and norepinephrine
What effects do tricyclic antidepressants have?
cardiotoxic effects
What is Baclofen indicated for?
spasticity
What is the mechanism of action of Valproic acid (Depakote)?
sodium channel inhibitor
Beta blockers act on the kidneys to decrease what?
renin release
Ace inhibitors producea more profound decrease in blood pressures
than angiotensin receptor antagonist because?
they decrease concentration of angiotensin II
What is an adverse reaction of ACE inhibitors?
cough
The heart pumps more efficiently when the patient is on digoxin
because the drug does what?
,Increases force of contraction and decreases the rate of contraction
What class of antibiotics are used with caution in patients that take
statins?
Erythromycins
Ezetimibe (Zetia) mechanism does what?
cholesterol absorption inhibitor
How does Gemfibrozil (Lopid) controls the synthesis of lipoprotein
metabolzing enzymes?
Binds to a DNA transcription regulator
Compelling indications for an ACE inhibitor as treatment for
hypertension based on clinical trials includes:
1. Pregnancy
2. Renal parenchymal disease
3. Stable angina
4. Dyslipidemia
Renal parenchymal disease
ACE inhibitors are the drug of choice for treating hypertension in
diabetic patients because they:
Improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
What does the provider understand about the issue of diabetic renal
protection with ACE? Diabetic patients:
Have a reduced rate of renal progression but still need to be discontinued
when advanced renal issues present.
Angioedema: a potentially life-threatening adverse response to ace
inhibitors is angioedema. Which of the following is true about this
adverse reaction?
Swelling of the tongue or hoarseness are the most common symptoms
Prior to developing a plan for the treatment of asthma, the patient's
asthma should be classified according to the NHLBI Expert Panel 3
guidelines. In adults mild-persistent asthma is classified as asthma
symptoms that occur:
1. Daily
2. Daily and limit physical activity
3. Less than twice a week
, 4. More than twice a week and less than once a day
More than twice a week and less than once a day
One goal of asthma therapy outlined by the NHLBI Expert Panel 3
guidelines is:
1. Ability to use albuterol daily to control symptoms
2. Minimize exacerbations to once a month
3. Keep nighttime symptoms at a maximum of twice a week
4. Require infrequent use of beta 2 agonists (albuterol) for relief of
symptoms
Require infrequent use of beta 2 agonists for relief of symptoms
Asthma exacerbations at home are managed by:
Increasing the frequency of beta 2 agonists and contacting their provider
One goal of asthma management in children is:
1. They independently manage their asthma
2. Participation in school and sports activities
3. No exacerbations
4. Minimal use of inhaled corticosteroids
Participation in school and sports activities
Pregnant patients with asthma may safely use throughout their
pregnancy:
Inhaled corticosteroids (budesonide)
Martin, a 60-year-old patient with hypertension, first line decongestant
to prescribe would be:
Nasal oxymetazoline
Education for patients who use inhaled beta agonists and inhaled
corticosteroids include:
Use the inhaled beta 2 agonists first followed by inhaled corticosteroids
What medication is used in CHF?
Spironolactone
Nitrate acts on the heart to do what?
decrease workload by reducing preload
What calcium channel blocker can be used with a beta blocker?
Amlodipine (Norvasc)
Why do calcium channel blockers have different tissue selectivity?
They bind to calcium channels in different tissues
What is recommended therapy for intermittent asthma?
short acting beta agonist
What is the mechanism of action of albuterol (Proventil)?
