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NR 507 ADVANCED PATHOPHYSIOLOGY MIDTERM EXAM
What does smooth muscle hypertrophy do in lungs?
Answer- causes increased bronchoconstriction
Hypertrophy and hyperplasia of goblet cells do what in the
bronchial
Answer- promotes hypersecretion of mucus
What are characteristics of epithelial cell metaplasia?
Answer- squamous cells become conciliated and are less
protective; allow passage of toxins and WBCs
,What does the migration of WBCs to the bronchial do?
Answer- increases inflammation of the cite and causes fibrosis
in the bronchial wall
How does the thickening and rigidity of bronchial basement
membranes effect the lungs?
Answer leads to further narrowing of the bronchial passageways
What acid-base disorder is seen in chronic bronchitis?
Answer- respiratory acidosis
how does chronic bronchitis lead to respiratory acidosis?
Answer- hyperinflation of the alveoli causes CO2 retention
Where does air enter the body?
Answer- naos and oropharynx (mouth and nose)
,Where does air go after it passes through the nose and mouth?
Answer- it passes through the trachea
After air passes through the trachea where does it go?
Answer- goes into the left or right bronchi
Where does air flow after the bronchi?
Answer- into the smaller bronchioles
Where does air flow after the bronchioles?
Answer- into the alveoli
Describe how blood flows to become oxygenated
- deoxygenated systemic blood flows from the vena cava to R
atrium
, - Tricuspid valve opens to flow to R ventricle
-Pulmonary semilunar valve opens and blood flows to the
alveolar capillaries for gas exchange from the pulmonary trunk
and L & R pulmonary arteries
- blood goes from alveolar capillaries to pulmonary veins to
return oxygenated blood to the left atrium
- bicuspid valve opens to allow blood to go to left ventricle
- aortic semilunar valve opens and blood goes to the aorta
- aorta pushes oxygenated blood out to the body
What is the formula for cardiac output?
Answer- CO = HR x SV
cardiac reserve
answer- difference between resting and maximal CO; should be
about 4-5x as high but does decrease 1% per year after age 30