UNIVERSITY Comprehensive
Questions with Verified
Answers Graded A+
Which of the types of chemical bonding between drugs and their receptors is the least
common? - Answer: Covalent
Which type of drug classification is most important to the practitioner? - Answer: Therapeutic
Mechanism of Action - Answer: The manner in which molecular targets are affected by the drug
Adverse Drug Reaction (ADR) can lead the patient to - Answer: stop taking the drug
Half-life is defined as - Answer: The time required for the plasma concentration of a drug to be
reduced by 50 percent
When one drug is more efficacious than another, it has... - Answer: A greater ability to initiate a
response
What is bioavailability? - Answer: The fraction of unchanged drug that reaches the systemic
circulation following administration by any route
, Absorption is defined as: - Answer: The transfer of a drug from its site of administration to the
blood
How can Competitive antagonism be overcome? - Answer: by adding more agonist
How is children's dosing most often calculated? - Answer: MG/KG
A patient complains of pain from a migraine. How would the practitioner classify this type of
pain? - Answer: Central Neuropathic Pain
What stage of nociception is occurring when neurotransmitters in the dorsal horn directly or
indirectly depolarize the second-order neurons? - Answer: Trasmission
What are the four processes of Nociception - Answer: transduction, transmission, modulation,
and perception
A practitioner conducting a pain assessment asks the patient, "Is the pain consistent or
intermittent?" What character of pain is the practitioner assessing? - Answer: Temporal pattern
What is the maximum dose of acetaminophen in 24 hours? - Answer: 4 grams
Etodolac is in the same drug class as ibuprofen. What is its mechanism of action? - Answer: It
inhibits the cyclooxygenase enzyme.
What kind of drug is Naloxone (Narcan) - Answer: opioid antagonist
Acetaminophen and alcohol have a complex relationship in the liver. Why? (3 reasons) - Answer:
1. They are both metabolized by the same liver enzyme.