| COMPLETE QUESTIONS & ANSWERS
(100% VERIFIED SOLUTIONS) LATEST UPDATE
1. What factors will place the patient at - Overuse of broad-spectrum antibiotics
risk for antibiotic resistance? - Multiple medical comorbidities
- Immunosuppression
- Antibiotic use in agriculture
- Complexity of medical procedures
- Children: exposure to children and daycare
2. Explain bacterial mechanisms of resis- - Decreased Permeability/Limiting Drug Uptake:
tance to antibacterial medications. Bacteria can alter their cell walls to prevent drugs
from entering.
- Antibiotic Efflux Pump: Bacteria can actively
pump out antibiotics, reducing drug concentra-
tion inside the cell.
- Drug Inactivation: Bacteria can produce en-
zymes that inactivate the antibiotic.
- Altered Target Site: Bacteria can modify the
drug's target site, reducing the drug's ettective-
ness.
3. What factors place the patient at risk - Hx of anaphylactic reaction to PCN
for hypersensitivity reactions with peni- - Cross-sensitivity is low for cephalosporins but
cillins and cephalosporins? caution is advised.
4. What are the safest antibiotics to pre- - PCNs and macrolides (azithromycin)
scribe to a woman who is pregnant? - Caution with amoxicillin d/t GI upset and skin
rash w/ viral illness
5. Which antibiotics inhibit bacterial cell bactericidal
wall synthesis? - Carbapenems
- Glycopeptides
- Monobactams
- Penicillins
, | COMPLETE QUESTIONS & ANSWERS
(100% VERIFIED SOLUTIONS) LATEST UPDATE
- Cephalosporins
- Fosfomycin
6. Why is clavulanate added to amoxicillin? broaden its spectrum of coverage and reduce
resistance
7. What antibiotics are appropriate to pre- - Erythromycin
scribe to children? - Azithromycin
- Amoxicillin
- Ceftriaxone
- Clindamycin
- Levofloxacin
8. What patient teaching will you provide - stay hydrated and monitor for severe symp-
to a patient who is experiencing non-in- toms.
fectious diarrhea related to antibiotic - If symptoms persist or worsen, they should con-
administration? tact their healthcare provider. - report any signs
of superinfection or severe diarrhea, as it may
indicate C. ditt.
9. What is an antibiogram? a document developed by hospital systems us-
ing cultured bacterial samples from clients to
determine regional bacterial resistance patterns
against antibiotics
10. A patient is taking a fluoroquinolone. - ADRs: tendonitis/tendon rupture, worsen-
What are the most serious adverse ef- ing MG, mental health adverse ettects, hypo-
fects? What are the risk factors for glycemia.
these adverse effects? Explain the side - Risk factors: age, hepatic/renal impairment, use
effects, considering what a patient of corticosteroids.
would need to know. - Education: stop medication & notify provider
if tendon tenderness presents. Avoid use in
OB/Peds.
, | COMPLETE QUESTIONS & ANSWERS
(100% VERIFIED SOLUTIONS) LATEST UPDATE
11. What population should not be admin- - Peds <8, OB/Lact.
istered tetracyclines and why? - Peds: can deposit in bones and teeth, leading
to permanent staining.
- OB: can attect fetal development, particularly
the teeth and bones of the fetus. - Caution is
also advised in individuals with renal or hepatic
impairment.
12. A patient is administered gentamicin immediately discontinue the medication and
and complains of sudden hearing loss. consult with an otolaryngologist for further eval-
What should the nurse practitioner do? uation and management. Monitoring renal func-
tion and drug levels may also be necessary.
13. Which medications interact with linezol- medications that increase serotonin levels, such
id? as SSRIs, SNRIs, and MAOIs, potentially leading
to serotonin syndrome
14. What is the course of treatment with Prophylaxis: 200 mg PO once. Tx: 100 mg q12h
doxycycline for the treatment of Lyme x7 days.
disease?
15. What are the main side effects of doxy- - N/V/D, anorexia, LH, vertigo, photosensitivity,
cycline? Explain the side effects, con- skin reactions
sidering what a patient would need to - Food, milk, and calcium decrease absorption.
know. - Avoid in hepatic/renal impairment,
OB/Lact/Peds <8
16. Differentiate between oral and par- - PO: primarily used to treat C. diflcile infections
enteral vancomycin. due to its poor absorption in the gastrointestinal
tract, making it ettective for localized treatment in
the gut.
- Parenteral (IV) vancomycin is used for serious
(100% VERIFIED SOLUTIONS) LATEST UPDATE
1. What factors will place the patient at - Overuse of broad-spectrum antibiotics
risk for antibiotic resistance? - Multiple medical comorbidities
- Immunosuppression
- Antibiotic use in agriculture
- Complexity of medical procedures
- Children: exposure to children and daycare
2. Explain bacterial mechanisms of resis- - Decreased Permeability/Limiting Drug Uptake:
tance to antibacterial medications. Bacteria can alter their cell walls to prevent drugs
from entering.
- Antibiotic Efflux Pump: Bacteria can actively
pump out antibiotics, reducing drug concentra-
tion inside the cell.
- Drug Inactivation: Bacteria can produce en-
zymes that inactivate the antibiotic.
- Altered Target Site: Bacteria can modify the
drug's target site, reducing the drug's ettective-
ness.
3. What factors place the patient at risk - Hx of anaphylactic reaction to PCN
for hypersensitivity reactions with peni- - Cross-sensitivity is low for cephalosporins but
cillins and cephalosporins? caution is advised.
4. What are the safest antibiotics to pre- - PCNs and macrolides (azithromycin)
scribe to a woman who is pregnant? - Caution with amoxicillin d/t GI upset and skin
rash w/ viral illness
5. Which antibiotics inhibit bacterial cell bactericidal
wall synthesis? - Carbapenems
- Glycopeptides
- Monobactams
- Penicillins
, | COMPLETE QUESTIONS & ANSWERS
(100% VERIFIED SOLUTIONS) LATEST UPDATE
- Cephalosporins
- Fosfomycin
6. Why is clavulanate added to amoxicillin? broaden its spectrum of coverage and reduce
resistance
7. What antibiotics are appropriate to pre- - Erythromycin
scribe to children? - Azithromycin
- Amoxicillin
- Ceftriaxone
- Clindamycin
- Levofloxacin
8. What patient teaching will you provide - stay hydrated and monitor for severe symp-
to a patient who is experiencing non-in- toms.
fectious diarrhea related to antibiotic - If symptoms persist or worsen, they should con-
administration? tact their healthcare provider. - report any signs
of superinfection or severe diarrhea, as it may
indicate C. ditt.
9. What is an antibiogram? a document developed by hospital systems us-
ing cultured bacterial samples from clients to
determine regional bacterial resistance patterns
against antibiotics
10. A patient is taking a fluoroquinolone. - ADRs: tendonitis/tendon rupture, worsen-
What are the most serious adverse ef- ing MG, mental health adverse ettects, hypo-
fects? What are the risk factors for glycemia.
these adverse effects? Explain the side - Risk factors: age, hepatic/renal impairment, use
effects, considering what a patient of corticosteroids.
would need to know. - Education: stop medication & notify provider
if tendon tenderness presents. Avoid use in
OB/Peds.
, | COMPLETE QUESTIONS & ANSWERS
(100% VERIFIED SOLUTIONS) LATEST UPDATE
11. What population should not be admin- - Peds <8, OB/Lact.
istered tetracyclines and why? - Peds: can deposit in bones and teeth, leading
to permanent staining.
- OB: can attect fetal development, particularly
the teeth and bones of the fetus. - Caution is
also advised in individuals with renal or hepatic
impairment.
12. A patient is administered gentamicin immediately discontinue the medication and
and complains of sudden hearing loss. consult with an otolaryngologist for further eval-
What should the nurse practitioner do? uation and management. Monitoring renal func-
tion and drug levels may also be necessary.
13. Which medications interact with linezol- medications that increase serotonin levels, such
id? as SSRIs, SNRIs, and MAOIs, potentially leading
to serotonin syndrome
14. What is the course of treatment with Prophylaxis: 200 mg PO once. Tx: 100 mg q12h
doxycycline for the treatment of Lyme x7 days.
disease?
15. What are the main side effects of doxy- - N/V/D, anorexia, LH, vertigo, photosensitivity,
cycline? Explain the side effects, con- skin reactions
sidering what a patient would need to - Food, milk, and calcium decrease absorption.
know. - Avoid in hepatic/renal impairment,
OB/Lact/Peds <8
16. Differentiate between oral and par- - PO: primarily used to treat C. diflcile infections
enteral vancomycin. due to its poor absorption in the gastrointestinal
tract, making it ettective for localized treatment in
the gut.
- Parenteral (IV) vancomycin is used for serious
